Intracerebroventricular administration of metformin inhibits ghrelin-induced Hypothalamic AMP-kinase signalling and food intake. (Q48655114)

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23 January 2020

title

Intracerebroventricular administration of metformin inhibits ghrelin-induced Hypothalamic AMP-kinase signalling and food intake (English)

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23 January 2020

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2

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23 January 2020

Ljubica Vucicevic

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23 January 2020

Maja Misirkic

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author name string

Darko Stevanovic

1

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23 January 2020

Mirjana Sumarac-Dumanovic

5

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Dragan Micic

6

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Vesna Starcevic

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23 January 2020

Vladimir Trajkovic

8

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publication date

14 February 2012

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23 January 2020

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23 January 2020

volume

96

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23 January 2020

page(s)

24-31

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issue

1

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Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview

23 January 2020

cites work

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Metformin and body weight

21 January 2018

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Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30.

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Effect of metformin on nitric oxide synthase in genetically obese (ob/ob) mice

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Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes.

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Metformin reduces body weight gain and improves glucose intolerance in high-fat diet-fed C57BL/6J mice

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Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide.

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Metformin restores leptin sensitivity in high-fat-fed obese rats with leptin resistance

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The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression.

21 January 2018

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Metformin inhibits adenosine 5'-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons.

21 January 2018

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AMPK: a key regulator of energy balance in the single cell and the whole organism.

21 January 2018

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The importance of regulation of blood glucose levels through activation of peripheral 5'-AMP-activated protein kinase on ischemic neuronal damage

21 January 2018

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A role for ghrelin in the central regulation of feeding

21 January 2018

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Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats.

21 January 2018

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Ghrelin induces adiposity in rodents

21 January 2018

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Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein

21 January 2018

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Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.

21 January 2018

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AMP-activated protein kinase plays a role in the control of food intake

21 January 2018

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

21 January 2018

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Mediobasal hypothalamic p70 S6 kinase 1 modulates the control of energy homeostasis

21 January 2018

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The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.

21 January 2018

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Hypothalamic mTOR signaling regulates food intake

21 January 2018

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Metformin increases plasma ghrelin in Type 2 diabetes

21 January 2018

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Long-term recording of cerebrospinal fluid pressure in freely behaving rats.

21 January 2018

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Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism.

21 January 2018

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Hypothalamic CaMKK2 contributes to the regulation of energy balance

21 January 2018

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Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin

21 January 2018

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The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin

21 January 2018

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Rapid rewiring of arcuate nucleus feeding circuits by leptin.

21 January 2018

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Metabolic regulation of neuronal plasticity by the energy sensor AMPK

21 January 2018

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AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

21 January 2018

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Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status

21 January 2018

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Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach

21 January 2018

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Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

21 January 2018

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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

21 January 2018

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Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

21 January 2018

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Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender

21 January 2018

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Clinical Pharmacokinetics of Metformin

21 January 2018

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