Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome. (Q48703968)

14 February 2018

title

Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome. (English)

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14 February 2018

author name string

Franz Herzog

series ordinal

1

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14 February 2018

Jan-Michael Peters

series ordinal

2

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14 February 2018

language of work or name

English

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publication date

1 January 2005

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14 February 2018

published in

Methods in Enzymology

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14 February 2018

volume

398

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14 February 2018

page(s)

175-195

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14 February 2018

Ionization-reactivity relationships for cysteine thiols in polypeptides.

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Temporal and spatial control of cyclin B1 destruction in metaphase

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The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae

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Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

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Tissue sulfhydryl groups

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Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

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Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

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Three-dimensional structure of the anaphase-promoting complex

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7 January 2021

Cyclin is degraded by the ubiquitin pathway

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Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

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The anaphase-promoting complex: it's not just for mitosis any more.

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Identification of Cell Cycle‐Dependent Phosphorylation Sites on the Anaphase‐Promoting Complex/Cyclosome by Mass Spectrometry

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7 January 2021

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

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Mitotic regulation of the human anaphase-promoting complex by phosphorylation

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Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

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Mitotic regulation of the APC activator proteins CDC20 and CDH1

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The spindle checkpoint: structural insights into dynamic signalling

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

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The anaphase-promoting complex: proteolysis in mitosis and beyond

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Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27

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Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

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The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

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APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

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CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

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Cell cycle: Waiters serving the Destruction machinery

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TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1

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p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase

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Requirement of the SCFPop1/Pop2 Ubiquitin Ligase for Degradation of the Fission Yeast S Phase Cyclin Cig2.

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Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes

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Raising Xenopus in the laboratory

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Identifiers

DOI

1 reference

14 February 2018

1 reference

14 February 2018