Synthesis and evaluation of [18F] labeled benzamides: high affinity sigma receptor ligands for PET imaging. (Q48710526)

14 February 2018

title

Synthesis and evaluation of [18F] labeled benzamides: high affinity sigma receptor ligands for PET imaging. (English)

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14 February 2018

author name string

Dence CS

1

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14 February 2018

John CS

2

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Bowen WD

3

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Welch MJ

4

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14 February 2018

publication date

1 May 1997

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14 February 2018

Nuclear Medicine and Biology

published in

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14 February 2018

volume

24

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issue

4

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page(s)

333-340

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14 February 2018

Autoradiographic localization of sigma receptor binding sites in guinea pig and rat central nervous system with (+)3H-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine

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A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain

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Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.

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An improved synthesis of [125I]N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma

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Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells

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Sigma receptors are expressed in human non-small cell lung carcinoma

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Regional variation in the ratio of sigma 1 to sigma 2 binding in rat brain

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The use of [18F]4-fluorobenzyl iodide (FBI) in PET radiotracer synthesis: Model alkylation studies and its application in the design of dopamine D1 and D2 receptor-based imaging agents

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Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brain

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(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (sigma 1) site and quantitative structure-affinity relationship studies

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(+)-[C-11]-cis-N-benzyl-normetazocine: a selective ligand for sigma receptors in vivo

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A proposal for the classification of sigma binding sites

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Separation of [18F]fluoride from [18O]water using anion exchange resin

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Sigma and opioid receptors in human brain tumors

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Evidence for a role of haloperidol-sensitive sigma-'opiate' receptors in the motor effects of antipsychotic drugs

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Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary

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7 January 2021

10.1016/S0969-8051(97)00001-2

Identifiers

DOI

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14 February 2018

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14 February 2018