Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. (Q48723929)

http://europepmc.org/abstract/MED/9096141

15 February 2018

title

Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. (English)

1 reference

http://europepmc.org/abstract/MED/9096141

15 February 2018

1 reference

1 reference

Z Pang

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

J W Geddes

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 May 1997

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http://europepmc.org/abstract/MED/9096141

15 February 2018

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

volume

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

page(s)

3064-3073

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

15 May 2020

cites work

1 reference

12 December 2020

Suppression of Mitochondrial Succinate Dehydrogenase, a Primary Target of β‐Amyloid, and Its Derivative Racemized at Ser Residue

1 reference

12 December 2020

Metabolic and energetic changes during apoptosis in neural cells

1 reference

12 December 2020

A selective toxicity toward cultured mesencephalic dopaminergic neurons is induced by the synergistic effects of energetic metabolism impairment and NMDA receptor activation.

1 reference

12 December 2020

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1 reference

12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

12 December 2020

Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis.

1 reference

12 December 2020

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

12 December 2020

Cell death: the significance of apoptosis

1 reference

12 December 2020

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

12 December 2020

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

12 December 2020

Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis

1 reference

12 December 2020

Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate

1 reference

12 December 2020

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

12 December 2020

Mitochondrial dysfunction is a primary event in glutamate neurotoxicity

1 reference

12 December 2020

Relation between mitochondrial calcium transport and control of energy metabolism

1 reference

12 December 2020

Substrate-dependent effects of calcium on rat retinal mitochondrial respiration: physiological and toxicological studies.

1 reference

12 December 2020

Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis

1 reference

12 December 2020

A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells.

1 reference

12 December 2020

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

1 reference

12 December 2020

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

1 reference

12 December 2020

Neurochemistry and toxin models in Huntington's disease.

1 reference

12 December 2020

Oxidative stress induces apoptosis in embryonic cortical neurons.

1 reference

12 December 2020

Alcohol inhibits the depolarization-induced stimulation of oxidative phosphorylation in synaptosomes

1 reference

12 December 2020

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

12 December 2020

3-Nitropropionic acid induces apoptosis in cultured striatal and cortical neurons.

1 reference

12 December 2020

Changes in mitochondrial function induced in isolated guinea-pig ventricular myocytes by calcium overload

1 reference

12 December 2020

A new enzymatic cycling technique for glutamate determination in brain microdialysates.

1 reference

12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Glutamate triggers internucleosomal DNA cleavage in neuronal cells

1 reference

12 December 2020

Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease

1 reference

12 December 2020

Apoptosis, oncosis, and necrosis. An overview of cell death

1 reference

12 December 2020

1 reference

12 December 2020

Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

1 reference

12 December 2020

Control of apoptosis by the cellular ATP level

1 reference

12 December 2020

3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum.

1 reference

12 December 2020

Glutamate-induced neuronal death is not a programmed cell death in cerebellar culture.

1 reference

12 December 2020

Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

1 reference

12 December 2020

Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition

1 reference

12 December 2020

Dopamine has inhibitory and accelerating effects on ischemia-induced neuronal cell damage in the rat striatum.

1 reference

12 December 2020

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

12 December 2020

Mitochondrial DNA mutations in diseases of energy metabolism

1 reference

12 December 2020

Trinucleotide repeats in neurologic diseases: an hypothesis concerning the pathogenesis of Huntington's disease, Kennedy's disease, and spinocerebellar ataxia type I.

1 reference

12 December 2020

Apoptosis in focal cerebral ischemia.

1 reference

12 December 2020

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

12 December 2020

Striatal protection induced by lesioning the substantia nigra of rats subjected to focal ischemia

1 reference

12 December 2020

Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

1 reference

12 December 2020

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

12 December 2020

Energy and glutamate dependency of 3-Nitropropionic acid neurotoxicity in culture

1 reference

12 December 2020

DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures.

1 reference

12 December 2020

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

1 reference

12 December 2020

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

12 December 2020

Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis?

1 reference

12 December 2020

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1 reference

12 December 2020

Neurotoxic and neurotrophic effects of chronic N-methyl-D-aspartate exposure upon mesencephalic dopaminergic neurons in organotypic culture

1 reference

12 December 2020

Delayed application of aurintricarboxylic acid reduces glutamate-induced cortical neuronal injury.

1 reference

12 December 2020

Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose.

1 reference

12 December 2020

3-Nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons

1 reference

12 December 2020

Calcium: still center-stage in hypoxic-ischemic neuronal death

1 reference

12 December 2020

Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.

1 reference

12 December 2020

Amyloid beta-mediated oxidative and metabolic stress in rat cortical neurons: no direct evidence for a role for H2O2 generation.

1 reference

12 December 2020

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1 reference

12 December 2020

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

1 reference

12 December 2020

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

12 December 2020

Mitochondria and programmed cell death: back to the future.

1 reference

12 December 2020

The mitochondrial inhibitor malonate enhances NMDA toxicity in the neonatal rat striatum

1 reference

12 December 2020

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

12 December 2020

10.1523/JNEUROSCI.17-09-03064.1997

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573656&resulttype=core&format=json

15 May 2020

1 reference