Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966. (Q48794762)

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1 November 2019

title

Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9030635%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1

J D Jentsch

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1 November 2019

author name string

J D Elsworth

2

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15 May 2020

D E Redmond

3

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R H Roth

4

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15 May 2020

J D Jentsch

1

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15 May 2020

language of work or name

English

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publication date

1 March 1997

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1 November 2019

published in

Journal of Neuroscience

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15 May 2020

volume

17

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issue

5

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15 May 2020

page(s)

1769-1775

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The NMDA glycine site antagonist (+)-HA-966 selectively regulates conditioned stress-induced metabolic activation of the mesoprefrontal cortical dopamine but not serotonin systems: a behavioral, neuroendocrine, and neurochemical study in the rat.

15 May 2020

cites work

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12 December 2020

Effect of Phencyclidine in Chronic Schizophrenics

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Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo

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Effects of CNS stimulants on the in vivo release of the colocalized transmitters, dopamine and neurotensin, from rat prefrontal cortex

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Diazepam antagonizes effects on dopamine metabolism produced by pcp receptor agonists

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12 December 2020

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative

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12 December 2020

Effects of cocaine and footshock stress on extracellular dopamine levels in the medial prefrontal cortex.

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The control of firing pattern in nigral dopamine neurons: single spike firing

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Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia

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12 December 2020

Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response

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12 December 2020

Model psychoses and schizophrenia

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12 December 2020

Regional brain catecholamines and metabolites following THC, PCP and MK-801

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12 December 2020

The control of firing pattern in nigral dopamine neurons: burst firing

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12 December 2020

Blockade by benzodiazepines of the selective high increase in dopamine turnover induced by stress in mesocortical dopaminergic neurons of the rat.

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12 December 2020

Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: antagonism by diazepam

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12 December 2020

Recent advances in the phencyclidine model of schizophrenia

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12 December 2020

NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine.

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12 December 2020

Dopamine and spatial working memory in rats and monkeys: pharmacological reversal of stress-induced impairment.

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12 December 2020

Stress-induced increase in 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the cerebral cortex and in n. accumbens: Reversal by diazepam

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12 December 2020

Competitive NMDA receptor antagonists attenuate phencyclidine-induced excitations of A10 dopamine neurons

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12 December 2020

The excitatory amino acid antagonist kynurenate induces pacemaker-like firing of dopamine neurons in rat ventral tegmental area in vivo

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12 December 2020

Effects of phencyclidine on the spontaneous activity of monoaminergic neurons.

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12 December 2020

The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents

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12 December 2020

Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966

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12 December 2020

The regulation of subcortical dopamine systems by the prefrontal cortex: interactions of central dopamine systems and the pathogenesis of schizophrenia.

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12 December 2020

Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry

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12 December 2020

Study of a new schizophrenomimetic drug; sernyl.

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12 December 2020

Extracellular dopamine and neurotensin in rat prefrontal cortex in vivo: effects of median forebrain bundle stimulation frequency, stimulation pattern, and dopamine autoreceptors

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12 December 2020

Phencyclidine and the midbrain dopamine system: electrophysiology and behavior

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12 December 2020

Selective activation of mesocortical DA system by stress

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12 December 2020

Excitatory amino acid-induced excitation of dopamine-containing neurons in the rat substantia nigra: modulation by kynurenic acid

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12 December 2020

Effects of diazepam on regional brain homovanillic acid following phencyclidine or delta 9-tetrahydrocannabinol.

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12 December 2020

Effects of the enantiomers of (+/-)-HA-966 on dopamine neurons: an electrophysiological study of a chiral molecule

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12 December 2020

On central muscle relaxants, strychnine-insensitive glycine receptors and two old drugs: zoxazolamine and HA-966

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12 December 2020

Delta 9-tetrahydrocannabinol increases prefrontal cortical catecholaminergic utilization and impairs spatial working memory in the rat: blockade of dopaminergic effects with HA966.

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12 December 2020

Effect of phencyclidine on dopamine release in the rat prefrontal cortex; an in vivo microdialysis study

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12 December 2020

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

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12 December 2020

Opiate actions on mesocortical dopamine metabolism in the rat.

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12 December 2020

Responses of rat substantia nigra dopamine-containing neurones to (-)-HA-966 in vitro

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12 December 2020

Stress activation of mesocorticolimbic dopamine neurons: effects of a glycine/NMDA receptor antagonist

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12 December 2020

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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12 December 2020

The case of frontostriatal dysfunction in schizophrenia.

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12 December 2020

Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys

1 reference

12 December 2020

Protein measurement with the Folin phenol reagent

1 reference

12 December 2020

10.1523/JNEUROSCI.17-05-01769.1997

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573388&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573388&resulttype=core&format=json

15 May 2020

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