Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. (Q48915866)

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8 December 2019

title

Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter (English)

1 reference

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8 December 2019

main subject

transmembrane protein

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serotonin

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author name string

E L Barker

1

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8 December 2019

K R Moore

2

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8 December 2019

F Rakhshan

3

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8 December 2019

R D Blakely

4

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8 December 2019

language of work or name

English

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publication date

1 June 1999

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8 December 2019

published in

Journal of Neuroscience

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8 December 2019

volume

19

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8 December 2019

issue

12

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8 December 2019

page(s)

4705-4717

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describes a project that uses

8 December 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain

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A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter

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Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants.

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Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands.

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Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation

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Human norepinephrine transporter. Biosynthetic studies using a site-directed polyclonal antibody

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Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium

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Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

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Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies.

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Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition

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Allele-specific activation of genetically engineered receptors

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Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence.

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H+ permeation and pH regulation at a mammalian serotonin transporter.

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Cloning and expression of a functional serotonin transporter from rat brain

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The activity of 25 paroxetine/femoxetine structure variants in various reactions, assumed to be important for the effect of antidepressants.

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Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter

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Determination of external loop topology in the serotonin transporter by site-directed chemical labeling

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Norepinephrine transporters have channel modes of conduction

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The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release

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Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression

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12 December 2020

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

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12 December 2020

The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding

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12 December 2020

Cocaine and the serotonin saga.

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12 December 2020

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12 December 2020

Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transporters

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Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

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12 December 2020

Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter

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From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters

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Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.

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12 December 2020

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12 December 2020

Analysis of the transmembrane topology and membrane assembly of the GAT-1 gamma-aminobutyric acid transporter.

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12 December 2020

Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel.

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12 December 2020

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12 December 2020

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12 December 2020

Affinity modulation of [3H]imipramine, [3H]paroxetine and [3H]citalopram binding to the 5-HT transporter from brain and platelets

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12 December 2020

Binding of the cocaine analog 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane to serotonin and dopamine transporters: different ionic requirements for substrate and 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane binding.

1 reference

12 December 2020

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

12 December 2020

10.1523/JNEUROSCI.19-12-04705.1999

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366604%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10366604%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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