Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons (Q48967524)

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scientific article published in January 2014

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English	Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons	scientific article published in January 2014

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

0 references

author name string

Xiaorui Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

Zsombor Lacza

2

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

Yi E Sun

3

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

Weiping Han

4

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

publication date

1 January 2014

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

57

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

1

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

236-245

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

The Central Melanocortin System and Energy Homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Serum immunoreactive-leptin levels are increased in patients with Cushing's syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Monogenic obesity in humans

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Absence of mutations in the human OB gene in obese/diabetic subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Activation of downstream signals by the long form of the leptin receptor

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Recent advances in understanding leptin signaling and leptin resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Proopiomelanocortin gene expression and DNA methylation: implications for Cushing's syndrome and beyond

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: a mechanism linking maternal undernutrition to obesity in the offspring?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

MeCP2, a key contributor to neurological disease, activates and represses transcription

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Tissue-specific activity of the pro-opiomelanocortin gene promoter

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

MECP2 is highly mutated in X-linked mental retardation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Preserved speech variants of the Rett syndrome: molecular and clinical analysis.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

De novo MECP2 frameshift mutation in a boy with moderate mental retardation, obesity and gynaecomastia.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

A novel hypomorphic MECP2 point mutation is associated with a neuropsychiatric phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Epigenetic mechanisms in the development of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Linking DNA methylation and histone modification: patterns and paradigms

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-013-3072-0

21 January 2018

Leptin signaling in the hypothalamus of normal rats in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/24078059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24078059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-013-3072-0

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 February 2018

http://europepmc.org/abstract/MED/24078059

ResearchGate publication ID

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