Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. (Q49032278)

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1 November 2019

title

Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study (English)

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4

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Hubertus Adrianus Marie Kerstjens

1 November 2019

5

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Dirkje S Postma

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1 November 2019

author name string

Johan C Kips

1

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1 November 2019

Brian J O'Connor

2

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1 November 2019

Stephen J Langley

3

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Mel Danzig

7

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Francis Cuss

8

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Romain A Pauwels

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language of work or name

English

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publication date

20 March 2003

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American Journal of Respiratory and Critical Care Medicine

1 November 2019

published in

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volume

167

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issue

12

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page(s)

1655-1659

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Asthma. From bronchoconstriction to airways inflammation and remodeling

1 November 2019

cites work

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A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma.

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Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia

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Serum interleukin 5 concentrations in atopic and non-atopic patients with glucocorticoid-dependent chronic severe asthma

21 January 2018

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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

21 January 2018

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Neutralizing monoclonal antibodies can potentiate IL-5 signaling

21 January 2018

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Eosinophilia, parasite burden and lung damage in Toxocara canis infection in C57Bl/6 mice genetically deficient in IL-5.

21 January 2018

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The central role of CD4(+) T cells in the antitumor immune response

21 January 2018

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Expression of oncoproteins and the amount of eosinophilic and lymphocytic infiltrates can be used as prognostic factors in gastric cancer. Dutch Gastric Cancer Group (DGCG).

21 January 2018

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Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

21 January 2018

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Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle

21 January 2018

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The IL-5 receptor on human bronchus selectively primes for hyperresponsiveness

21 January 2018

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Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma

21 January 2018

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Effect of acute and chronic antigen inhalation on airway morphology and responsiveness in actively sensitized rats

21 January 2018

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Airway eosinophilia is not a requirement for allergen-induced airway hyperresponsiveness.

21 January 2018

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Asymptomatic worsening of airway inflammation during low-dose allergen exposure in asthma: protection by inhaled steroids

21 January 2018

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The trials and tribulations of IL-5, eosinophils, and allergic asthma

21 January 2018

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10.1164/RCCM.200206-525OC

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12649124%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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