Mouse models of alpha-synucleinopathy and Lewy pathology. (Q49158678)

18 February 2018

title

Mouse models of alpha-synucleinopathy and Lewy pathology. (English)

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18 February 2018

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Sommer B

1

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18 February 2018

Barbieri S

2

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18 February 2018

Hofele K

3

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Wiederhold K

4

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Probst A

5

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Mistl C

6

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Danner S

7

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Kauffmann S

8

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Spooren W

9

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Tolnay M

10

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Bilbe G

11

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van der Putten H

12

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Kafmann S

13

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Caromi P

14

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Ruegg MA

15

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publication date

1 December 2000

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18 February 2018

published in

Experimental Gerontology

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volume

35

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issue

9-10

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page(s)

1389-1403

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18 February 2018

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies

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Extensive axonal Lewy neurites in Parkinson's disease: a novel pathological feature revealed by alpha-synuclein immunocytochemistry

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Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system

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Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

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Synthetic filaments assembled from C-terminally truncated alpha-synuclein.

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From entropy to Duino

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Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

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A Drosophila model of Parkinson's disease

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Neuropathology of Parkinson's disease

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Ubiquitin-positive degenerating neurites in the brainstem in Parkinson's disease

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Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

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Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity.

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Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein

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Axonal transport of synucleins is mediated by all rate components

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Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

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7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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7 January 2021

Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease.

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7 January 2021

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

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7 January 2021

A new stain for quantitative measurement of sprouting at neuromuscular junctions

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7 January 2021

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7 January 2021

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7 January 2021

Alpha-synuclein in Lewy bodies

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7 January 2021

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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7 January 2021

Neuropathology in mice expressing human alpha-synuclein

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7 January 2021

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

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7 January 2021

Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy.

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7 January 2021

Neuron-specific transgene expression of Bcl-XL but not Bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice

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7 January 2021

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

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7 January 2021

10.1016/S0531-5565(00)00181-9

Identifiers

DOI

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18 February 2018

PubMed ID

11113617

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18 February 2018