Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. (Q49160789)

18 February 2018

title

Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. (English)

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18 February 2018

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3

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author name string

Adám Dénes

1

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18 February 2018

Szilamér Ferenczi

2

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18 February 2018

Zsuzsanna Környei

4

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18 February 2018

Krisztina J Kovács

5

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18 February 2018

publication date

25 June 2008

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18 February 2018

Journal of Cerebral Blood Flow & Metabolism

published in

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18 February 2018

volume

28

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issue

10

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18 February 2018

page(s)

1707-1721

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18 February 2018

Neuronal 'On' and 'Off' signals control microglia

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CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.

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Proliferating resident microglia after focal cerebral ischaemia in mice.

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

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Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

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Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

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A novel role of interleukin-1-converting enzyme in cytokine-mediated inducible nitric oxide synthase gene expression: Implications for neuroinflammatory diseases.

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Production of monocyte chemoattractant protein-1 and cytokine-induced neutrophil chemoattractant-1 in rat brain is stimulated by intracerebroventricular administration of an endothelin ETB receptor agonist.

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Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

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Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis

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Sensory inattention in rats with 6-hydroxydopamine-induced degeneration of ascending dopaminergic neurons: Apomorphine-induced reversal of deficits

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Systemic inflammation and stroke: aetiology, pathology and targets for therapy.

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Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

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Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine

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Inflammation and ischaemic stroke.

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GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue.

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Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice

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Mast cells migrate, but do not degranulate, in response to fractalkine, a membrane-bound chemokine expressed constitutively in diverse cells of the skin

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Posture-independent sensorimotor analysis of inter-hemispheric receptor asymmetries in neostriatum

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7 January 2021

Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury.

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7 January 2021

Expression of fractalkine and its receptor, CX3CR1, in response to ischaemia-reperfusion brain injury in the rat.

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Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release.

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7 January 2021

Potential mechanisms of interleukin-1 involvement in cerebral ischaemia.

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7 January 2021

Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor.

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No role for interleukin-18 in acute murine stroke-induced brain injury.

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7 January 2021

Fractalkine upregulates intercellular adhesion molecule-1 in endothelial cells through CX3CR1 and the Jak Stat5 pathway.

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7 January 2021

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

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Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures

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7 January 2021

Post-ischemic inflammation: molecular mechanisms and therapeutic implications

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7 January 2021

Identifiers

DOI

10.1038/JCBFM.2008.64

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18 February 2018

PubMed ID

18575457

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18 February 2018