Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG. (Q50097559)

24 February 2018

title

Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG. (English)

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main subject

Salmonella Typhimurium

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10

Gordon Dougan

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author name string

Nicola D McKelvie

1

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Richard Stratford

2

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Tao Wu

3

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Trevor Bellaby

4

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Emma Aldred

5

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Nicky J Hughes

6

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Steven N Chatfield

7

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Derek Pickard

8

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Christine Hale

9

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Shahid A Khan

11

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language of work or name

English

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publication date

1 September 2004

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24 February 2018

published in

Vaccine

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volume

22

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issue

25-26

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page(s)

3243-3255

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Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine

cites work

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Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity

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Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium

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Fluorescence-based isolation of bacterial genes expressed within host cells

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Construction of broad-host-range plasmid vectors for easy visible selection and analysis of promoters

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Further characterization of Escherichia coli brain microvascular endothelial cell invasion gene ibeA by deletion, complementation, and protein expression

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Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains.

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Generation of a cytotoxic T-lymphocyte response using a Salmonella antigen-delivery system

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Stability, immunogenicity and expression of foreign antigens in bacterial vaccine vectors.

7 January 2021

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A Salmonella typhimurium virulence protein is similar to a Yersinia enterocolitica invasion protein and a bacteriophage lambda outer membrane protein

7 January 2021

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Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes

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Salmonella typhi and S typhimurium derivatives harbouring deletions in aromatic biosynthesis and Salmonella Pathogenicity Island-2 (SPI-2) genes as vaccines and vectors.

7 January 2021

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Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers.

7 January 2021

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pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium.

7 January 2021

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Oral vaccination against tetanus: comparison of the immunogenicities of Salmonella strains expressing fragment C from the nirB and htrA promoters.

7 January 2021

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Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var. Typhimurium

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Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector

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Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis

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Identifiers

DOI

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24 February 2018

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24 February 2018