Casein kinase 1 epsilon (Q5014192)

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mammalian protein found in Homo sapiens
  • LOC400927-CSNK1E
  • uniprot:P49674
  • CKIe
  • CKI-epsilon
  • casein kinase I isoform epsilon
  • CSNK1E
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Language Label Description Also known as
English
Casein kinase 1 epsilon
mammalian protein found in Homo sapiens
  • LOC400927-CSNK1E
  • uniprot:P49674
  • CKIe
  • CKI-epsilon
  • casein kinase I isoform epsilon
  • CSNK1E

Statements

molecular function
protein serine/threonine kinase activity
determination method
IDA
TAS
IEA
6 references
retrieved
17 October 2017
stated in
Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
TAS
retrieved
17 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
TAS
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
IEA
retrieved
17 October 2017
stated in
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
IDA
retrieved
17 October 2017
stated in
Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P49674&geneProductId=UniProtKB:P49674
determination method
IDA
protein binding
determination method
IPI
20 references
retrieved
1 January 2018
stated in
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Modeling of a human circadian mutation yields insights into clock regulation by PER2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
A directed protein interaction network for investigating intracellular signal transduction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Identification of a novel Wnt5a-CK1É›-Dvl2-Plk1-mediated primary cilia disassembly pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
retrieved
1 January 2018
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IPI
protein serine/threonine kinase activity
determination method
IBA
IDA
IEA
TAS
6 references
retrieved
1 January 2018
stated in
Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
TAS
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
TAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IEA
retrieved
1 January 2018
stated in
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein
GOA
curator
UniProt
UniProt protein ID
P49674
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IDA
retrieved
1 January 2018
stated in
Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49674
determination method
IBA
cell component
biological process

Identifiers

Freebase ID
/m/03c9prh
0 references
 
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