In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram (Q50223962)

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scientific article published on 6 September 2006

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English	In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram	scientific article published on 6 September 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

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27 February 2018

http://europepmc.org/abstract/MED/16955282

Rupert Lanzenberger

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27 February 2018

http://europepmc.org/abstract/MED/16955282

Siegfried Kasper

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27 February 2018

http://europepmc.org/abstract/MED/16955282

Nilufar Mossaheb

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N Mossaheb

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N Klein

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PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

T Geiss-Granadia

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PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

T Attarbaschi

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27 February 2018

http://europepmc.org/abstract/MED/16955282

C Pötzi

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27 February 2018

http://europepmc.org/abstract/MED/16955282

A Holik

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27 February 2018

http://europepmc.org/abstract/MED/16955282

C Spindelegger

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27 February 2018

http://europepmc.org/abstract/MED/16955282

S Asenbaum

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27 February 2018

http://europepmc.org/abstract/MED/16955282

R Dudczak

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27 February 2018

http://europepmc.org/abstract/MED/16955282

J Tauscher

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27 February 2018

http://europepmc.org/abstract/MED/16955282

publication date

6 September 2006

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27 February 2018

http://europepmc.org/abstract/MED/16955282

Psychopharmacology

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27 February 2018

http://europepmc.org/abstract/MED/16955282

188

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27 February 2018

http://europepmc.org/abstract/MED/16955282

3

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27 February 2018

http://europepmc.org/abstract/MED/16955282

263-272

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27 February 2018

http://europepmc.org/abstract/MED/16955282

SPECT of serotonin transporters using 123I-ADAM: optimal imaging time after bolus injection and long-term test-retest in healthy volunteers.

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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?-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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Unique mechanism of action for escitalopram: does it hold the promise?

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study.

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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Measuring SSRI occupancy of SERT using the novel tracer [123I]ADAM: a SPECT validation study

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https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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SSRIs and SNRIs: broad spectrum of efficacy beyond major depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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In vivo visualization of serotonin transporters in the human brain during fluoxetine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

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2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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R-citalopram counteracts the antidepressant-like effect of escitalopram in a rat chronic mild stress model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective, multicentre, randomized, double-blind study of the efficacy of escitalopram versus citalopram in outpatient treatment of major depressive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Escitalopram versus citalopram: the surprising role of the R-enantiomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Lack of citalopram effect on oral digoxin pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant dissociation of brain and plasma kinetics with antipsychotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Transport mechanisms for the antidepressant citalopram in brain microvessel endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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R-citalopram counteracts the effect of escitalopram in a rat conditioned fear stress model of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biodistribution and radiation dosimetry of [123I]ADAM in healthy human subjects: preliminary results

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Suicide by antidepressant intoxication identified at autopsy in Vienna from 1991–1997: the favourable consequences of the increasing use of SSRIs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram (S-enantiomer of citalopram): clinical efficacy and onset of action predicted from a rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Stereoselective single-dose kinetics of citalopram and its metabolites in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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Onset of action of escitalopram compared with other antidepressants: results of a pooled analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

R-citalopram inhibits functional and 5-HTP-evoked behavioural responses to the SSRI, escitalopram

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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[123I]-beta-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

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The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of escitalopram in patients with severe depression: a pooled analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder--implications for psychopharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High affinity [3H]paroxetine binding to serotonin uptake sites in human brain tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of serotonin transporters in nonhuman primates using [(123)I]ADAM and SPECT.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple hormone responses to stimulation with dl-fenfluramine in patients with major depression before and after antidepressive treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram (10-20 mg/day) is effective and well tolerated in a placebo-controlled study in depression in primary care

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced serotonin type 1A receptor binding in panic disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

R-citalopram functionally antagonises escitalopram in vivo and in vitro: evidence for kinetic interaction at the serotonin transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16955282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-006-0486-0

1 reference

Europe PubMed Central

PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 February 2018

http://europepmc.org/abstract/MED/16955282

ResearchGate publication ID

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