Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa. (Q50284446)

1 March 2018

title

Anticoagulant activity of a sulfated galactan: serpin-independent effect and specific interaction with factor Xa. (English)

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1 March 2018

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Bianca F Glauser

1

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1 March 2018

Ricardo M Rezende

2

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1 March 2018

Fabio R Melo

3

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1 March 2018

Mariana S Pereira

4

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1 March 2018

Ivo M B Francischetti

5

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1 March 2018

Robson Q Monteiro

6

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1 March 2018

Alireza R Rezaie

7

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1 March 2018

Paulo A S Mourão

8

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1 March 2018

publication date

1 December 2009

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1 March 2018

Thrombosis and Haemostasis

published in

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1 March 2018

volume

102

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1 March 2018

issue

6

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1 March 2018

page(s)

1183-1193

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1 March 2018

Outbreak of adverse reactions associated with contaminated heparin

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Contaminated heparin associated with adverse clinical events and activation of the contact system

22 May 2018

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Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite

22 May 2018

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Sulfation patterns of glycosaminoglycans encode molecular recognition and activity

22 May 2018

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Ixolaris: a factor Xa heparin-binding exosite inhibitor

22 May 2018

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Searching for alternatives to heparin: sulfated fucans from marine invertebrates

22 May 2018

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Molecular mapping of the heparin-binding exosite of thrombin

22 May 2018

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Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors

22 May 2018

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A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma

22 May 2018

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Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis

22 May 2018

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Low molecular weight heparin in prevention of perioperative thrombosis

22 May 2018

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Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade.

22 May 2018

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An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases.

3 July 2018

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Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays

14 August 2018

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Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

14 August 2018

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Bothrojaracin, a proexosite I ligand, inhibits factor Va-accelerated prothrombin activation.

14 August 2018

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Hypersulfated low molecular weight heparin with reduced affinity for antithrombin acts as an anticoagulant by inhibiting intrinsic tenase and prothrombinase

14 August 2018

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Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa.

14 August 2018

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Structure and Anticoagulant Activity of Sulfated Galactans

14 August 2018

1 reference

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Identification of basic residues in the heparin-binding exosite of factor Xa critical for heparin and factor Va binding

30 November 2018

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12 December 2020

Heparins in the new millennium: will unfractionated heparin survive? Epilogue

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12 December 2020

Heparin-binding exosite of factor Xa

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12 December 2020

Dual effects of sulfated D-galactans from the red algae Botryocladia occidentalis preventing thrombosis and inducing platelet aggregation

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12 December 2020

Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans?

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12 December 2020

A 2-sulfated, 3-linked α-l-galactan is an anticoagulant polysaccharide

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12 December 2020

Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides

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12 December 2020

The mode of action of heparin in plasma

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12 December 2020

Effects of gamma-carboxyglutamic acid and epidermal growth factor-like modules of factor IX on factor X activation. Studies using proteolytic fragments of bovine factor IX

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12 December 2020

Inhibition by heparin of the human blood coagulation intrinsic pathway factor X activator

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12 December 2020

Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of

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12 December 2020

Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae

1 reference

12 December 2020

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of alpha-thrombin

1 reference

12 December 2020

Serpin-independent anticoagulant activity of a fucosylated chondroitin sulfate

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH09-04-0273

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1 March 2018

PMC publication ID

2791905

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1 March 2018

PubMed publication ID

19967150

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1 March 2018