Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. (Q50335870)

http://europepmc.org/abstract/MED/20483750

5 March 2018

title

Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6309988&resulttype=core&format=json

13 May 2020

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Johann Röhrl

1

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13 May 2020

De Yang

series ordinal

2

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13 May 2020

Joost J Oppenheim

series ordinal

3

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13 May 2020

Thomas Hehlgans

series ordinal

4

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13 May 2020

language of work or name

English

0 references

publication date

17 May 2010

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http://europepmc.org/abstract/MED/20483750

5 March 2018

published in

Journal of Immunology

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13 May 2020

volume

184

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13 May 2020

issue

12

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13 May 2020

page(s)

6688-6694

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

13 May 2020

cites work

1 reference

12 December 2020

Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia

1 reference

12 December 2020

CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium

1 reference

12 December 2020

The structure of human beta-defensin-2 shows evidence of higher order oligomerization

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12 December 2020

Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis

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12 December 2020

Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction

1 reference

12 December 2020

Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens

1 reference

12 December 2020

Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein

1 reference

12 December 2020

Defensins of vertebrate animals

1 reference

12 December 2020

Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse

1 reference

12 December 2020

The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

1 reference

12 December 2020

Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

1 reference

12 December 2020

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

1 reference

12 December 2020

Blood monocytes consist of two principal subsets with distinct migratory properties

1 reference

12 December 2020

IL-22 increases the innate immunity of tissues

1 reference

12 December 2020

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways

1 reference

12 December 2020

Identification of CCR2, flotillin, and gp49B genes as new G-CSF targets during neutrophilic differentiation

1 reference

12 December 2020

Alarmins: chemotactic activators of immune responses

1 reference

12 December 2020

CCR2 and CCR6, but not endothelial selectins, mediate the accumulation of immature dendritic cells within the lungs of mice in response to particulate antigen.

1 reference

12 December 2020

Chemokines direct endothelial progenitors into tumor neovessels

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12 December 2020

Cutting edge: human beta defensin 3--a novel antagonist of the HIV-1 coreceptor CXCR4.

1 reference

12 December 2020

Antimicrobial peptides human β-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability

1 reference

12 December 2020

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

1 reference

12 December 2020

Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines

1 reference

12 December 2020

IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.

1 reference

12 December 2020

Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.

1 reference

12 December 2020

Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3

1 reference

12 December 2020

Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

1 reference

12 December 2020

CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality

1 reference

12 December 2020

Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.

1 reference

12 December 2020

Tracing functional antigen-specific CCR6 Th17 cells after vaccination

1 reference

12 December 2020

Overexpression of human beta-defensin-3 in oral dysplasia: potential role in macrophage trafficking

1 reference

12 December 2020

Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.

1 reference

12 December 2020

Blockade of a chemokine, CCL2, reduces chronic colitis-associated carcinogenesis in mice.

1 reference

12 December 2020

Specific binding and chemotactic activity of mBD4 and its functional orthologue hBD2 to CCR6-expressing cells

1 reference

12 December 2020

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1 reference

12 December 2020

Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins

1 reference

12 December 2020

Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor.

1 reference

12 December 2020

Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils

1 reference

12 December 2020

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

1 reference

12 December 2020

Monomeric monocyte chemoattractant protein-1 (MCP-1) binds and activates the MCP-1 receptor CCR2B.

1 reference

12 December 2020

CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha.

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0903984

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6309988&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6309988&resulttype=core&format=json

13 May 2020

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