Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction. (Q50476357)

14 March 2018

title

Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction. (English)

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14 March 2018

author

Thomas Jentsch

12

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14 March 2018

Clara Vilches

object named as

Clara Vilches

8

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Miguel López de Heredia

object named as

Miguel López de Heredia

9

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Isidro Ferrer

4

object named as

Isidre Ferrer

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14 March 2018

author name string

Maja B Hoegg-Beiler

1

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14 March 2018

Sònia Sirisi

2

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14 March 2018

Ian J Orozco

3

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14 March 2018

Svea Hohensee

5

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14 March 2018

Muriel Auberson

6

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14 March 2018

Kathrin Gödde

7

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Virginia Nunes

10

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14 March 2018

Raúl Estévez

11

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14 March 2018

language of work or name

English

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publication date

19 March 2014

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14 March 2018

published in

Nature Communications

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14 March 2018

volume

5

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14 March 2018

page(s)

3475

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14 March 2018

Mutations of MLC1 (KIAA0027), encoding a putative membrane protein, cause megalencephalic leukoencephalopathy with subcortical cysts

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GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit

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7 January 2021

Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts

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7 January 2021

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Identifiers

DOI

10.1038/NCOMMS4475

1 reference

14 March 2018

ADS bibcode

2014NatCo...5.3475H

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14 March 2018