Synergistic effect of interleukin-2 and a vaccine of irradiated melanoma cells transfected to secrete staphylococcal enterotoxin A. (Q50488407)

14 March 2018

title

Synergistic effect of interleukin-2 and a vaccine of irradiated melanoma cells transfected to secrete staphylococcal enterotoxin A. (English)

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14 March 2018

author name string

David P Schrayer

1

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14 March 2018

Nicola Kouttab

2

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14 March 2018

Vincent J Hearing

3

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14 March 2018

Harold J Wanebo

4

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14 March 2018

publication date

1 January 2002

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14 March 2018

Clinical & Experimental Metastasis

published in

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14 March 2018

volume

19

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14 March 2018

issue

1

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page(s)

43-53

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14 March 2018

Generation of cytotoxic antibodies to the B16 murine melanoma using a formalinized vaccine.

cites work

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Induction of interleukin-2, natural killer cell activity and anti-melanoma antibodies resulting from immunization of mice with formalinized extracellular antigens (FECA) of murine melanoma

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Enhancement of antibody-dependent cellular cytotoxicity of neonatal cells by interleukin-2 (IL-2) and IL-12

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Costimulation regulates the kinetics of interleukin-2 response to bacterial superantigens

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Practical spontaneous metastasis model for in vivo therapeutic studies using a human melanoma

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Monoclonal antibody production to a B16 melanoma associated antigen.

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Improved immunotherapy of a recombinant carcinoembryonic antigen vaccinia vaccine when given in combination with interleukin-2

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Prevention of superantigen-induced down-regulation of T-cell mediated cytotoxic activity by IL-2 in vivo

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The effects of interleukin-2 on bone marrow engraftment in a murine model

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Immunization of mice with irradiated melanoma tumor cells transfected to secrete lymphokines and coupled with IL-2 or GM-CSF therapy.

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IL-2-mediated cell cycle progression and inhibition of apoptosis does not require NF-kappa B or activating protein-1 activation in primary human T cells.

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Study of activation of murine T cells with bacterial superantigens. In vitro induction of enhanced responses in CD4+ T cells and of anergy in CD8+ T cells

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B700 antigen as a component of an antimelanoma vaccine: formalinized extracellular antigens

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A new mouse model of experimental melanoma for vaccine and lymphokine therapy

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Modeling immunotherapy of the tumor-immune interaction.

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Preimmunization of mice with formalinized extracellular antigens of melanoma in combination with IL-2 and surgical resection increased survival and tumor control in metastatic melanoma model.

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Correlation of growth capacity of cells in hard agarose with successful transfection by the activated c-Ha-ras oncogene and in vivo proliferative capacity at metastatic sites

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12 December 2020

Transfection of interleukin 2 gene into human melanoma cells augments cellular immune response.

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12 December 2020

Immunization of mice with melanoma cells transfected to secrete the superantigen, staphylococcal enterotoxin A.

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12 December 2020

Functional characterization of the interaction between the superantigen staphylococcal enterotoxin A and the TCR

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12 December 2020

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

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12 December 2020

Differential response of CD4+ V7+ and CD4+ V7- T cells to T cell receptor-dependent signals: CD4+ V7+ T cells are co-stimulation independent and anti-V7 antibody blocks the induction of anergy by bacterial superantigen

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Demonstration of B700 cross-reactive antigens on human and other animal melanomas.

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Paracrine cytokine adjuvants in cancer immunotherapy

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12 December 2020

Antitumor effects of polyvalent and monovalent vaccines coupled with interleukin-2 in a metastatic melanoma model.

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12 December 2020

Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen

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Demonstration and isolation of murine melanoma-associated antigenic surface proteins

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H-2Kb transfection of B16 melanoma cells results in reduced tumourigenicity and metastatic competence

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12 December 2020

A stage-specific enhancer of immunoglobulin J chain gene is induced by interleukin-2 in a presecretor B cell stage

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Generation of effective cancer vaccines genetically engineered to secrete cytokines using adenovirus-enhanced transferrinfection (AVET)

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In vivo T-cell activation by staphylococcal enterotoxin B prevents outgrowth of a malignant tumor

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Further characterization of a clinically relevant model of melanoma metastasis and an effective vaccine

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In vitro and in vivo targeting of gene expression to melanoma cells

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12 December 2020

Immunotherapy of mice with an irradiated melanoma vaccine coupled with interleukin-12.

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12 December 2020

CD8+ cells are the main producers of IL10 and IFN gamma after superantigen stimulation

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12 December 2020

Effects of H-2Kb gene on expression of melanoma-associated antigen and lectin-binding sites on BL6 melanoma cells

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

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Murine melanoma-specific tumor rejection activity elicited by a purified, melanoma-associated antigen.

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12 December 2020

Interleukin 2-induced proliferation of murine natural killer cells in vivo

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12 December 2020

Proteinuria of B700, a 67 kD albumin-like melanoma-specific antigen.

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12 December 2020

Cross-linking of MHC class II molecules by staphylococcal enterotoxin A is essential for antigen-presenting cell and T cell activation

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12 December 2020

Production of monoclonal antibodies against the B700 murine melanoma antigen and their antimetastatic properties

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12 December 2020

Bacterial superantigens as anti-tumour agents: induction of tumour cytotoxicity in human lymphocytes by staphylococcal enterotoxin A.

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12 December 2020

Effect of continuous administration of interleukin 2 on active specific chemoimmunotherapy with extracted tumor-specific transplantation antigen and cyclophosphamide

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12 December 2020

The conventional CD4+ T cell response to staphylococcal enterotoxin B is modified by its superantigenic activity

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12 December 2020

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

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12 December 2020

Mutations in the MHC class II binding domains of staphylococcal enterotoxin A differentially affect T cell receptor Vbeta specificity

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12 December 2020

Exogenous interleukin 2 recruits in vitro lymphokine-activated killer activity by in vivo activated lymphocytes

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12 December 2020

Identifiers

DOI

10.1023/A:1013875104326

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14 March 2018

Dimensions Publication ID

1016635658

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14 March 2018