In vivo structure-function analyses of Caenorhabditis elegans MEC-4, a candidate mechanosensory ion channel subunit. (Q50497285)

PubMed publication ID

10729338

14 March 2018

http://europepmc.org/abstract/MED/10729338

title

In vivo structure-function analyses of Caenorhabditis elegans MEC-4, a candidate mechanosensory ion channel subunit (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772260&resulttype=core&format=json

12 May 2020

main subject

Caenorhabditis elegans

0 references

1 reference

K Hong

1

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12 May 2020

I Mano

series ordinal

2

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12 May 2020

M Driscoll

series ordinal

3

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12 May 2020

language of work or name

English

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publication date

1 April 2000

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PubMed publication ID

10729338

14 March 2018

http://europepmc.org/abstract/MED/10729338

published in

Journal of Neuroscience

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12 May 2020

volume

20

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issue

7

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12 May 2020

page(s)

2575-2588

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DEG/ENaC channels: a touchy superfamily that watches its salt

12 May 2020

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The molecules of mechanosensation.

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Caenorhabditis ElegansDegenerins and Vertebrate Enac Ion Channels Contain an Extracellular Domain Related to Venom Neurotoxins

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A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity

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Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach

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Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel

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A molecular component of the arterial baroreceptor mechanotransducer

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Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegans

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A pore segment in DEG/ENaC Na(+) channels.

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Chapter 14 Methods for the Study of Cell Death in the Nematode Caenorhabditis elegans

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Combinatorial control of touch receptor neuron expression in Caenorhabditis elegans

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Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel.

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A new member of the amiloride-sensitive sodium channel family in Drosophila melanogaster peripheral nervous system

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Interactions between subunits of the human epithelial sodium channel.

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Genetic control of differentiation of the Caenorhabditis elegans touch receptor neurons

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Effect of subunit composition and Liddle's syndrome mutations on biosynthesis of ENaC

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unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion

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The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans

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Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome

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A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel

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The Caenorhabditis elegans rol-6 gene, which interacts with the sqt-1 collagen gene to determine organismal morphology, encodes a collagen

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Mechanosensitivity of the epithelial sodium channel (ENaC): controversy or pseudocontroversy?

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The nematode degenerin UNC-105 forms ion channels that are activated by degeneration- or hypercontraction-causing mutations

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Functional degenerin-containing chimeras identify residues essential for amiloride-sensitive Na+ channel function

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12 December 2020

The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration

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Regulation of the epithelial Na+ channel by membrane tension

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Regulation of Caenorhabditis elegans degenerin proteins by a putative extracellular domain

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An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans

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12 December 2020

Epithelial sodium channels

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12 December 2020

Interaction between a putative mechanosensory membrane channel and a collagen

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12 December 2020

Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome

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Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans

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The genetics of Caenorhabditis elegans

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The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore

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Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

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H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels

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Touch receptor development and function in Caenorhabditis elegans

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12 December 2020

Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface

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Protons activate brain Na+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration.

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12 December 2020

Biophysical and molecular mechanisms of Shaker potassium channel inactivation

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Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans

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12 December 2020

Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation

1 reference

12 December 2020

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome

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12 December 2020

Potassium channels and their evolving gates

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12 December 2020

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system

1 reference

12 December 2020

A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans

1 reference

12 December 2020

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

1 reference

12 December 2020

Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel

1 reference

12 December 2020

On the molecular basis of ion permeation in the epithelial Na+ channel

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The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans

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12 December 2020

Mechanosensitive ion channels and their mode of activation

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12 December 2020

The NH(2) terminus of the epithelial sodium channel contains an endocytic motif

1 reference

12 December 2020

Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

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Organization of neuronal microtubules in the nematode Caenorhabditis elegans

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dGNaC1, a gonad-specific amiloride-sensitive Na+ channel

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12 December 2020

Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons.

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12 December 2020

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

1 reference

12 December 2020

A cloned renal epithelial Na+ channel protein displays stretch activation in planar lipid bilayers

1 reference

12 December 2020

The unc-8 and sup-40 genes regulate ion channel function in Caenorhabditis elegans motorneurons.

1 reference

12 December 2020

Identification of a highly conserved sequence at the N-terminus of the epithelial Na+ channel alpha subunit involved in gating

1 reference

12 December 2020

Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans

1 reference

12 December 2020

A single point mutation in the pore region of the epithelial Na+ channel changes ion selectivity by modifying molecular sieving.

1 reference

12 December 2020

Extracellular proteins needed for C. elegans mechanosensation

1 reference

12 December 2020

Mutations causing neurodegeneration in Caenorhabditis elegans drastically alter the pH sensitivity and inactivation of the mammalian H+-gated Na+ channel MDEG1.

1 reference

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Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities

1 reference

12 December 2020

10.1523/JNEUROSCI.20-07-02575.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772260&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772260&resulttype=core&format=json

12 May 2020

PubMed publication ID

10729338

1 reference