Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF). (Q50513227)

14 March 2018

title

Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF). (English)

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14 March 2018

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Woynarowska BA

1

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14 March 2018

Woynarowski JM

2

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14 March 2018

Herzig MC

3

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14 March 2018

Roberts K

4

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14 March 2018

Higdon AL

5

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14 March 2018

MacDonald JR

6

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14 March 2018

language of work or name

English

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publication date

1 May 2000

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14 March 2018

published in

Biochemical Pharmacology

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14 March 2018

volume

59

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14 March 2018

issue

10

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14 March 2018

page(s)

1217-1226

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14 March 2018

Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity

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Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents

7 January 2021

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Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114)

7 January 2021

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Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF)

7 January 2021

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DNA adducts from chemotherapeutic agents

7 January 2021

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Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells

7 January 2021

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NCM460, a normal human colon mucosal epithelial cell line

7 January 2021

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Pilocarpine, a salivary gland radioprotectant, does not inhibit cytotoxic effect of gamma-radiation on squamous cell carcinoma in vitro

7 January 2021

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New colorimetric cytotoxicity assay for anticancer-drug screening

7 January 2021

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Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.

7 January 2021

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Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53

7 January 2021

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p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.

7 January 2021

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bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells

7 January 2021

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Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response

7 January 2021

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Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

7 January 2021

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Growth slow-down and growth arrest of human colon carcinoma cells HCT-8 in vitro after exposure to 5-fluoro-2'-deoxyuridine

7 January 2021

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The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

7 January 2021

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Apoptosis- and necrosis-inducing potential of cladribine, cytarabine, cisplatin, and 5-fluorouracil in vitro: a quantitative pharmacodynamic model.

7 January 2021

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7 January 2021

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Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

7 January 2021

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The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

7 January 2021

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Thiol-mediated redox regulation of neutrophil apoptosis

7 January 2021

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Redox regulation of cellular signalling

7 January 2021

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Thioredoxin redox control of cell growth and death and the effects of inhibitors

7 January 2021

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

7 January 2021

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Interaction of quinones with Arabidopsis thaliana thioredoxin reductase

7 January 2021

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Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells

7 January 2021

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Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00254-9

1 reference

14 March 2018

release_o35w5wouirelfc46hanzttfdwe

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/o35w5wouirelfc46hanzttfdwe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 March 2018