Nonproteolytic role for the urokinase receptor in cellular migration in vivo. (Q50513823)

14 March 2018

title

Nonproteolytic role for the urokinase receptor in cellular migration in vivo. (English)

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14 March 2018

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Waltz DA

1

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Fujita RM

2

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Yang X

3

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Natkin L

4

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Zhuo S

5

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Gerard CJ

6

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Rosenberg S

7

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Chapman HA

8

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publication date

1 March 2000

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14 March 2018

American Journal of Respiratory Cell and Molecular Biology

published in

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volume

22

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issue

3

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page(s)

316-322

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Cell-associated plasminogen activation: regulation and physiological functions

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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

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The urokinase receptor is required for human monocyte chemotaxis in vitro

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Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

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A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

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Prevention of metastasis by inhibition of the urokinase receptor

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Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

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Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

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alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

21 January 2018

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Cytokines induce urokinase-dependent adhesion of human myeloid cells. A regulatory role for plasminogen activator inhibitors

21 January 2018

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Regulation of integrin function by the urokinase receptor

21 January 2018

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Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

21 January 2018

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The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells.

21 January 2018

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LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice

21 January 2018

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The directed migration of eukaryotic cells

21 January 2018

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Urokinase-type plasminogen activator-induced monocyte adhesion requires a carboxyl-terminal lysine and cAMP-dependent signal transduction

21 January 2018

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Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

21 January 2018

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Physiological consequences of loss of plasminogen activator gene function in mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1165/AJRCMB.22.3.3713

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14 March 2018

PubMed ID

10696068

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14 March 2018