The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells. (Q50521448)

14 March 2018

title

The adjuvant effect of TLR agonists on CD4(+) effector T cells is under the indirect control of regulatory T cells. (English)

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14 March 2018

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Aurélie Olivier

1

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14 March 2018

Alexander Sainz-Perez

2

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14 March 2018

Hui Dong

3

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14 March 2018

Tim Sparwasser

4

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14 March 2018

Laleh Majlessi

5

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14 March 2018

Claude Leclerc

6

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14 March 2018

language of work or name

English

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publication date

6 June 2011

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14 March 2018

European Journal of Immunology

published in

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14 March 2018

volume

41

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14 March 2018

issue

8

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14 March 2018

page(s)

2303-2313

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14 March 2018

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

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Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells

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Toll-like receptors on regulatory T cells: expanding immune regulation

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Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

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Toll-like receptor 2 controls expansion and function of regulatory T cells

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Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells

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Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

21 January 2018

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Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory Cells

21 January 2018

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Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal.

21 January 2018

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TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help.

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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

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Coordination of early protective immunity to viral infection by regulatory T cells

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

21 January 2018

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CD4+ CD25+ regulatory T cells control T helper cell type 1 responses to foreign antigens induced by mature dendritic cells in vivo

21 January 2018

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Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells

21 January 2018

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Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells

21 January 2018

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TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

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Regulatory T cells and Toll-like receptors: what is the missing link?

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Expression and function of Toll-like receptors in T lymphocytes

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Engagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survival

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The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

21 January 2018

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CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells

21 January 2018

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Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

21 January 2018

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Modulation of dendritic cell function by naive and regulatory CD4+ T cells

21 January 2018

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Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes

21 January 2018

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Toll-like receptor signalling on Tregs: to suppress or not to suppress?

21 January 2018

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Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells

21 January 2018

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Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes

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Therapeutic potential of Toll-like receptor 9 activation

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Regulatory T cells and toll-like receptors in cancer therapy

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Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors

21 January 2018

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Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

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Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines.

21 January 2018

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Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

21 January 2018

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Functional role of type I and type II interferons in antiviral defense

21 January 2018

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Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

21 January 2018

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Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation.

21 January 2018

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21 January 2018

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7 January 2021

Dendritic cells: translating innate to adaptive immunity.

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7 January 2021

Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells

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7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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7 January 2021

CD4+ CD25+ regulatory T cells control the magnitude of T-dependent humoral immune responses to exogenous antigens

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7 January 2021

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo

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7 January 2021

Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system

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7 January 2021

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

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7 January 2021

Human CD4+CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation

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7 January 2021

Identifiers

DOI

10.1002/EJI.201041387

1 reference

14 March 2018

1 reference

14 March 2018