Site-directed mutagenesis and expression of PC2 in microinjected Xenopus oocytes (Q50795969)

19 March 2018

title

Site-directed mutagenesis and expression of PC2 in microinjected Xenopus oocytes (English)

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site-directed mutagenesis

15 November 2022

main subject

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15 November 2022

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15 November 2022

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15 November 2022

5

Docherty K

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19 March 2018

K. I. Shennan

1

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15 November 2022

A. J. Seal

2

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15 November 2022

S. P. Smeekens

3

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15 November 2022

D. F. Steiner

4

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15 November 2022

language of work or name

English

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publication date

1 December 1991

1 reference

19 March 2018

15 December 1991

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1748673

full work available at URL

15 November 2022

http://intl.jbc.org/cgi/content/abstract/266/35/24011

online access status

open access

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https://api.elsevier.com/content/article/PII:S0021925818543842?httpAccept=text/xml

15 November 2022

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https://api.elsevier.com/content/article/PII:S0021925818543842?httpAccept=text/plain

15 November 2022

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https://api.crossref.org/works/10.1016/S0021-9258(18)54384-2

Journal of Biological Chemistry

15 November 2022

published in

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19 March 2018

volume

266

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19 March 2018

issue

35

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19 March 2018

page(s)

24011-24017

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19 March 2018

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

cites work

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A Film Detection Method for Tritium-Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

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Proceedings of the National Academy of Sciences of the United States of America

15 November 2022

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author name string

Brenner

publication date

1991

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Endopeptidases and prohormone processing

15 November 2022

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Post-translational proteolysis in polypeptide hormone biosynthesis

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The processing and secretion of rat serum albumin by oocytes from Xenopus laevis

15 November 2022

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15 November 2022

Carboxypeptidase E

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Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

15 November 2022

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Subtilisin-like proteinases involved in the activation of proproteins of the eukaryotic secretory pathway

15 November 2022

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Microinjected Xenopus oocytes secrete mature, biologically active parathyroid hormone

15 November 2022

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Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase

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Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

15 November 2022

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

15 November 2022

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The sequestration, processing and retention of honey-bee promelittin made in amphibian oocytes.

15 November 2022

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Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

15 November 2022

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Direct identification of prohormone conversion site in insulin-secreting cells

15 November 2022

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Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi

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Secretion and autoproteolytic maturation of subtilisin

15 November 2022

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Intracellular Compartmentation and Secretion of Carp Proinsulin Synthesized in Xenopus Oocytes

15 November 2022

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cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

15 November 2022

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Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

15 November 2022

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Expression of normal and mutant human pre-pro-insulins in Xenopus oocytes

15 November 2022

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Characterization of PC2, a mammalian Kex2 homologue, following expression of the cDNA in microinjected Xenopus oocytes

15 November 2022

31

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Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

15 November 2022

33

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Nature of Albumin Exported from the Frog Oocyte Following Microinjection of Mouse Liver mRNA

15 November 2022

34

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Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

15 November 2022

35

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15 November 2022

Identifiers

1 reference

19 March 2018