Nucleoporin 98-96kD Dmel_CG10198 (Q50846371)

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Protein found in Drosophila melanogaster

nucleoporin 96
CG10198-PD
CG10198-PC
Nup98
nucleoporin 98
nucleoporin 98-96
Nup98-96
CG10198-PA
CG10198 gene product from transcript CG10198-RA
Nup98-96-PA
Nup98-96-PC
nucleoporin98-96
Nup98-96-PD
nucleoporin 98-96kD

Language	Label	Description	Also known as
English	Nucleoporin 98-96kD Dmel_CG10198	Protein found in Drosophila melanogaster	nucleoporin 96 CG10198-PD CG10198-PC Nup98 nucleoporin 98 nucleoporin 98-96 Nup98-96 CG10198-PA CG10198 gene product from transcript CG10198-RA Nup98-96-PA Nup98-96-PC nucleoporin98-96 Nup98-96-PD nucleoporin 98-96kD

Statements

1 reference

25 May 2022

UniProt protein ID

Nuclear pore complex protein NUP98-NUP96

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VCH5

Peptidase S59, nucleoporin superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VCH5

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Nuclear protein 96 family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase S59, nucleoporin, protein family

1 reference

based on heuristic

inferred from protein domain or family

Nucleoporin FG repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

protein binding

determination method

5 references

8 April 2019

Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

nuclear localization sequence binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

serine-type peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

structural constituent of nuclear pore

determination method

chromatin DNA binding

determination method

3 references

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

promoter-specific chromatin binding

determination method

determination method

4 references

8 April 2019

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

4 references

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

4 references

8 April 2019

Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

polytene chromosome

determination method

1 reference

8 April 2019

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

polytene chromosome band

determination method

1 reference

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

nuclear membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

nuclear pore central transport channel

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

nuclear pore cytoplasmic filaments

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

biological process

posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

positive regulation of defense response to virus by host

determination method

1 reference

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCH5&geneProductId=UniProtKB:Q9VCH5

determination method

regulation of transcription, DNA-templated

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCH5&geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

protein import into nucleus

determination method

1 reference

27 March 2018

Specific nucleoporin requirement for Smad nuclear translocation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VCH5&geneProductId=UniProtKB:Q9VCH5

determination method

nucleocytoplasmic transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

protein transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

germ-line stem cell population maintenance

determination method

1 reference

8 April 2019

Nucleoporin98-96 function is required for transit amplification divisions in the germ line of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

positive regulation of actin filament polymerization

determination method

1 reference

8 April 2019

Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

telomere tethering at nuclear periphery

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

cellular response to heat

determination method

1 reference

8 April 2019

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

response to ecdysone

determination method

1 reference

8 April 2019

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

heat shock-mediated polytene chromosome puffing

determination method

1 reference

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

larval lymph gland hemopoiesis

determination method

1 reference

8 April 2019

Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

male germ-line stem cell population maintenance

determination method

1 reference

8 April 2019

Nucleoporin98-96 function is required for transit amplification divisions in the germ line of Drosophila melanogaster

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

negative regulation by host of viral transcription

determination method

1 reference

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

positive regulation of transcription by RNA polymerase II

determination method

4 references

8 April 2019

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

8 April 2019

Nucleoporin Nup98 associates with Trx/MLL and NSL histone-modifying complexes and regulates Hox gene expression.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

positive regulation of transcription initiation from RNA polymerase II promoter

determination method

1 reference

8 April 2019

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

cellular response to ecdysone

determination method

1 reference

8 April 2019

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VCH5

determination method

Peptidase S59, nucleoporin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VCH5

Nuclear protein 96

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VCH5

Nucleoporin FG repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VCH5

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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