Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study (Q50850482)

24 March 2018

title

Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study (English)

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cartilage development

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4

Poh S Lee

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author name string

Quinn Harris

1

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Jonathan Seto

2

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Kate O'Brien

3

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Colleen Kondo

5

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Bryan J Heard

6

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David A Hart

7

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Roman J Krawetz

8

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publication date

1 October 2013

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published in

Stem Cells

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volume

31

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issue

10

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page(s)

2253-2265

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The prevalence and burden of arthritis

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Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.

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In vitro generation of a scaffold-free tissue-engineered construct (TEC) derived from human synovial mesenchymal stem cells: biological and mechanical properties and further chondrogenic potential

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Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit.

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Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source

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Mesenchymal progenitor cells derived from synovium and infrapatellar fat pad as a source for superficial zone cartilage tissue engineering: analysis of superficial zone protein/lubricin expression

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Synovium-derived mesenchymal stem cells: a new cell source for musculoskeletal regeneration.

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Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells.

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Wound healing in MIP-1alpha(-/-) and MCP-1(-/-) mice

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Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells.

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Stromal cell-derived factor-1 and monocyte chemotactic protein-3 improve recruitment of osteogenic cells into sites of musculoskeletal repair.

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Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies

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Cytokines as therapeutic targets for osteoarthritis

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Synovial tissue inflammation in early and late osteoarthritis

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Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism

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Interleukin-1beta and tumor necrosis factor alpha inhibit chondrogenesis by human mesenchymal stem cells through NF-kappaB-dependent pathways

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Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties.

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Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells

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Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture

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Osteoblasts suppress high bone turnover caused by osteolytic breast cancer in-vitro

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A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation

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Human chondrocytes express functional chemokine receptors and release matrix-degrading enzymes in response to C-X-C and C-C chemokines

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Inhalation of carbon monoxide ameliorates collagen-induced arthritis in mice and regulates the articular expression of IL-1beta and MCP-1.

21 January 2018

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An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

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L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer

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Chondrogenic differentiation of human mesenchymal stem cells using a thermosensitive poly(N-isopropylacrylamide) and water-soluble chitosan copolymer.

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Sustained Wnt protein expression in chondral constructs from mesenchymal stem cells

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Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation.

21 January 2018

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JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression

21 January 2018

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Interleukin 6 induces monocyte chemoattractant protein-1 expression in myeloma cells

21 January 2018

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Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1.

21 January 2018

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Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1

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In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells.

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Multilineage potential of adult human mesenchymal stem cells

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Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease

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Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands

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Bone Marrow Cells Immunomagnetically Selected For CD271+ Antigen Promote In Vitro the Repair of Articular Cartilage Defects

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21 January 2018

Identifiers

DOI

10.1002/STEM.1477

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24 March 2018

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24 March 2018