Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction. (Q51011345)

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scientific article published on 4 May 2007

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English	Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction.	scientific article published on 4 May 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction. (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

rheumatoid arthritis

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based on heuristic

inferred from title

dimensionality reduction

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based on heuristic

inferred from title

2

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Marylyn D. Ritchie

6

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Marylyn Ritchie

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

author name string

Antonio Julià

1

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Laia Miquel

3

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Cayetano Alegre

4

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Pere Barceló

5

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

Sara Marsal

7

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

publication date

4 May 2007

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

90

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

1

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

6-13

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

A question of transformation: the synovial fibroblast in rheumatoid arthritis

1 reference

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Synovial fibroblasts: key players in rheumatoid arthritis

1 reference

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Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.

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NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes

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Regional analysis of p53 mutations in rheumatoid arthritis synovium

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Reverse engineering gene regulatory networks.

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Modular epistasis in yeast metabolism.

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Reverse engineering of regulatory networks in human B cells

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Novel tumor necrosis factor alpha-regulated genes in rheumatoid arthritis.

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Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands

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Evolving concepts of rheumatoid arthritis

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Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

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A global view of epistasis

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Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

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7 January 2021

Computational inference of transcriptional regulatory networks from expression profiling and transcription factor binding site identification

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7 January 2021

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions

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7 January 2021

A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

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NF-kappaB: a key role in inflammatory diseases

1 reference

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7 January 2021

An essential role of NF-kappaB in the "tumor-like" phenotype of arthritic synoviocytes

1 reference

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7 January 2021

NF-kappaB: Holy Grail for rheumatoid arthritis?

1 reference

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7 January 2021

Identification of three related human GRO genes encoding cytokine functions

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7 January 2021

Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor

1 reference

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7 January 2021

Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2

1 reference

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7 January 2021

Keratinocyte-specific modulation of type VII collagen gene expression by pro-inflammatory cytokines (tumor necrosis factor-alpha and interleukin-1beta).

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7 January 2021

The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes

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7 January 2021

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

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7 January 2021

Interleukin 4-induced gene 1 is activated in primary mediastinal large B-cell lymphoma

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SINK Is a p65-interacting Negative Regulator of NF-κB-dependent Transcription

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7 January 2021

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

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7 January 2021

Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice.

1 reference

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7 January 2021

Two-loci interaction confirms arthritis-regulating quantitative trait locus on rat chromosome 6.

1 reference

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7 January 2021

The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis

1 reference

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7 January 2021

Epistatic modeling in rheumatoid arthritis: an application of the Risch theory

1 reference

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The effect of HLA–DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin α–tumor necrosis factor haplotype

1 reference

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Epistatic interaction between FCRL3 and NFkappaB1 genes in Spanish patients with rheumatoid arthritis

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IL-6 promoter polymorphisms in rheumatoid arthritis

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Second class minors: molecular identification of the autosomal H46 histocompatibility locus as a peptide presented by major histocompatibility complex class II molecules

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Activin A induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.

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Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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Tests and estimates of allelic association in complex inheritance

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Lack of association between the corticotropin-releasing hormone locus and rheumatoid arthritis

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The structure of haplotype blocks in the human genome

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Model-free analysis and permutation tests for allelic associations.

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Identifiers

10.1016/J.YGENO.2007.03.011

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/17482423

ResearchGate publication ID

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