The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. (Q51033843)

27 March 2018

title

The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4. (English)

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27 March 2018

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Yu-Rong Weng

1

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27 March 2018

Xuan Kong

2

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27 March 2018

Ya-Nan Yu

3

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27 March 2018

Ying-Chao Wang

4

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27 March 2018

Jie Hong

5

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27 March 2018

Shu-Liang Zhao

6

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27 March 2018

Jing-Yuan Fang

7

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27 March 2018

publication date

26 April 2013

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27 March 2018

published in

Molecular Carcinogenesis

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27 March 2018

volume

53 Suppl 1

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27 March 2018

page(s)

E72-84

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27 March 2018

Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology

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The genetics of colorectal cancer

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The MAPK signalling pathways and colorectal cancer

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Mutations of the BRAF gene in human cancer

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

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Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic

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The SMS domain of Trs23p is responsible for the in vitro appearance of the TRAPP I complex in Saccharomyces cerevisiae.

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TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion

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Identification and characterization of five new subunits of TRAPP.

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TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport

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Crystal structure of human synbindin reveals two conformations of longin domain

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Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda

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A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly

21 January 2018

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TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells

21 January 2018

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Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

21 January 2018

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Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma

21 January 2018

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Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation

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hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers

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How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

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ERK1/2 MAP kinases: structure, function, and regulation

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

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The Hallmarks of Cancer

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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

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Targeting the RAS pathway in melanoma

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Mutants in trs120 disrupt traffic from the early endosome to the late Golgi

21 January 2018

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Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

21 January 2018

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Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway

21 January 2018

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Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae

21 January 2018

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Lost in transcription: p21 repression, mechanisms, and consequences

21 January 2018

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The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

21 January 2018

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Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK

21 January 2018

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The role of Trs65 in the Ypt/Rab guanine nucleotide exchange factor function of the TRAPP II complex

21 January 2018

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TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF.

21 January 2018

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ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf

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21 January 2018

Identifiers

DOI

10.1002/MC.22031

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27 March 2018

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27 March 2018