Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative (Q51037995)

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scientific article published on September 9, 2010

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English	Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative	scientific article published on September 9, 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative (English)

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10.1177/0269881110379286

https://api.crossref.org/works/10.1177/0269881110379286

10 July 2024

Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20829307

10 July 2024

5

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Tangui Maurice

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20829307

10 July 2024

author name string

Vanessa Villard

1

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

Julie Espallergues

2

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

Emeline Keller

3

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

Alexandre Vamvakides

4

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

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publication date

9 September 2010

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

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http://journals.sagepub.com/doi/pdf/10.1177/0269881110379286

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10.1177/0269881110379286

https://api.crossref.org/works/10.1177/0269881110379286

10 July 2024

http://journals.sagepub.com/doi/full-xml/10.1177/0269881110379286

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10.1177/0269881110379286

https://api.crossref.org/works/10.1177/0269881110379286

10 July 2024

Journal of Psychopharmacology

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

25

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Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

8

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

1101-1117

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors

1 reference

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21 January 2018

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit

1 reference

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21 January 2018

Facilitation of memory storage by the acetylcholine M2 muscarinic receptor antagonist AF-DX 116.

1 reference

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21 January 2018

Pregnancy reduces brain sigma receptor function

1 reference

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21 January 2018

Neurosteroid enhances glutamate release in rat prelimbic cortex via activation of alpha1-adrenergic and sigma1 receptors

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21 January 2018

The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected beta-amyloid in the rat brain

1 reference

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21 January 2018

Involvement of the sigma1 (sigma1) receptor in the anti-amnesic, but not antidepressant-like, effects of the aminotetrahydrofuran derivative ANAVEX1-41.

1 reference

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21 January 2018

Cholinergic-mediated IP3-receptor activation induces long-lasting synaptic enhancement in CA1 pyramidal neurons.

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21 January 2018

Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence

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21 January 2018

Therapeutic strategies in Alzheimer's disease: M1 muscarinic agonists

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M<sub>1</sub> Muscarinic Agonists Can Modulate Some of the Hallmarks in Alzheimer's Disease: Implications in Future Therapy

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21 January 2018

Regulating ankyrin dynamics: Roles of sigma-1 receptors

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21 January 2018

Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

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21 January 2018

High occupancy of sigma1 receptors in the human brain after single oral administration of donepezil: a positron emission tomography study using [11C]SA4503.

1 reference

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21 January 2018

TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons

1 reference

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21 January 2018

Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.

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21 January 2018

Galantamine modulates nicotinic receptor and blocks Abeta-enhanced glutamate toxicity

1 reference

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21 January 2018

Muscarinic receptor 1 agonist activity of novel N-arylthioureas substituted 3-morpholino arecoline derivatives in Alzheimer's presenile dementia models

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21 January 2018

Reactive oxygen species regulate signaling pathways induced by M1 muscarinic receptors in PC12M1 cells

1 reference

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21 January 2018

Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity.

1 reference

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21 January 2018

The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.

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21 January 2018

Increase of extracellular acetylcholine level in rat frontal cortex induced by (+)N-allylnormetazocine as measured by brain microdialysis

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21 January 2018

SA4503, a novel cognitive enhancer, with sigma 1 receptor agonistic properties.

1 reference

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21 January 2018

The pharmacology of sigma-1 receptors

1 reference

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21 January 2018

Behavioral evidence for a modulating role of sigma ligands in memory processes. I. Attenuation of dizocilpine (MK-801)-induced amnesia

1 reference

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21 January 2018

Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors

1 reference

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21 January 2018

Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction

1 reference

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21 January 2018

Interaction with sigma(1) protein, but not N-methyl-D-aspartate receptor, is involved in the pharmacological activity of donepezil

1 reference

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21 January 2018

Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: pharmacological evidence and therapeutic opportunities

1 reference

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21 January 2018

Sigma1 (sigma 1) receptor agonists and neurosteroids attenuate B25-35-amyloid peptide-induced amnesia in mice through a common mechanism.

1 reference

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21 January 2018

Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB

1 reference

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21 January 2018

The anti-amnesic and neuroprotective effects of donepezil against amyloid beta25-35 peptide-induced toxicity in mice involve an interaction with the sigma1 receptor

1 reference

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21 January 2018

The sigma1 protein as a target for the non-genomic effects of neuro(active)steroids: molecular, physiological, and behavioral aspects

1 reference

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21 January 2018

Intracellular sigma1 receptor modulates phospholipase C and protein kinase C activities in the brainstem

1 reference

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21 January 2018

Central muscarinic activities of an M1-selective agonist: preferential effect on reversal of amnesia

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21 January 2018

Blockade of hippocampal M1 muscarinic receptors impairs working memory performance of rats

1 reference

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21 January 2018

Memory deficits and increased emotionality induced by beta-amyloid (25-35) are correlated with the reduced acetylcholine release and altered phorbol dibutyrate binding in the hippocampus

1 reference

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21 January 2018

Neurotransmitter receptor plasticity in aging

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21 January 2018

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

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21 January 2018

Muscarinic and nicotinic modulation of cortical acetylcholine release monitored by in vivo microdialysis in freely moving adult rats

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21 January 2018

The molecular pathology of Alzheimer's disease

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21 January 2018

Reduction of the scopolamine-induced impairment of passive-avoidance performance by sigma receptor agonist in mice.

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21 January 2018

Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats

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21 January 2018

Amyloid beta peptide 25-35 modulates hydrolysis of phosphoinositides by membrane phospholipase(s) C of adult brain cortex

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21 January 2018

Tacrine and donepezil attenuate the neurotoxic effect of A beta(25-35) in rat PC12 cells.

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Antiamnesic and neuroprotective effects of the aminotetrahydrofuran derivative ANAVEX1-41 against amyloid beta(25-35)-induced toxicity in mice

1 reference

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Animal models of Alzheimer's disease and evaluation of anti-dementia drugs

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Muscarinic acetylcholine receptors: signal transduction through multiple effectors.

9

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10 July 2024

Acta Neurologica Scandinavica

37

49

13

author name string

Mohammed AH

publication date

1993

1 reference

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10 July 2024

Beneficial effects of FKS-508 (AF102B), a selective M1 agonist, on the impaired working memory in AF64A-treated rats.

42

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Changes in phosphoinositide signalling activity and levels of the alpha subunit of G(q/11) protein in rat brain induced by E-5842, a sigma(1) receptor ligand and potential atypical antipsychotic

48

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10 July 2024

Identifiers

10.1177/0269881110379286

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 March 2018

http://europepmc.org/abstract/MED/20829307

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