A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest. (Q51089795)

29 March 2018

title

A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest. (English)

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29 March 2018

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Casini T

1

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29 March 2018

Pelicci PG

series ordinal

2

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29 March 2018

language of work or name

English

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publication date

1 May 1999

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29 March 2018

published in

Oncogene

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29 March 2018

volume

18

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29 March 2018

issue

21

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29 March 2018

page(s)

3235-3243

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29 March 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202630

exact match

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cites work

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Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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WAF1, a potential mediator of p53 tumor suppression

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The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

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Histone acetylation in chromatin structure and transcription

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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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New functional activities for the p21 family of CDK inhibitors

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

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Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

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Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5

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Cell cycle dependence of laminar determination in developing neocortex

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Role of DNA replication in the repression of silent mating type loci in yeast

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The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

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Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development

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p21 is a universal inhibitor of cyclin kinases

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p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

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Phosphorylation and activation of B-Myb by cyclin A-Cdk2.

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Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesis

21 January 2018

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

21 January 2018

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7 January 2021

Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control

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7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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7 January 2021

Proliferation is required for induction of terminal differentiation of Friend erythroleukemia cells

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202630

1 reference

29 March 2018

PubMed ID

10359529

1 reference

29 March 2018