Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. (Q51138513)

10 June 2018

title

Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. (English)

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10 June 2018

1 reference

Avinash Kumar

1

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10 June 2018

Gangarao Davuluri

2

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10 June 2018

Rafaella Nascimento E Silva

3

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10 June 2018

Marielle P K J Engelen

4

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10 June 2018

Gabrie A M Ten Have

5

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10 June 2018

Richard Prayson

6

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10 June 2018

Nicolaas E P Deutz

7

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10 June 2018

Srinivasan Dasarathy

8

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10 June 2018

language of work or name

English

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publication date

28 April 2017

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10 June 2018

published in

Hepatology

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10 June 2018

volume

65

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10 June 2018

issue

6

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10 June 2018

page(s)

2045-2058

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10 June 2018

Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis

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14 June 2018

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Hyperammonemia results in reduced muscle function independent of muscle mass.

14 June 2018

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Expression of ammonia transporters Rhbg and Rhcg in mouse skeletal muscle and the effect of 6-week training on these proteins

14 June 2018

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Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

14 June 2018

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Alcohol-induced autophagy contributes to loss in skeletal muscle mass

14 June 2018

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Post-liver transplantation sarcopenia in cirrhosis: a prospective evaluation

14 June 2018

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Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism

14 June 2018

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Branched-chain amino acids and ammonia metabolism in liver disease: therapeutic implications

14 June 2018

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Ammonia-lowering strategies for the treatment of hepatic encephalopathy.

14 June 2018

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Consilience in sarcopenia of cirrhosis

14 June 2018

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Rifaximin, but not growth factor 1, reduces brain edema in cirrhotic rats.

14 June 2018

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Malnutrition in cirrhosis: contribution and consequences of sarcopenia on metabolic and clinical responses

14 June 2018

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Sarcopenia associated with portosystemic shunting is reversed by follistatin

14 June 2018

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Sarcopenia and mortality after liver transplantation.

14 June 2018

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Ammonia: a diffusible factor released by proliferating cells that induces autophagy

14 June 2018

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Efficacy of L-ornithine L-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study

14 June 2018

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Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

14 June 2018

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Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients

14 June 2018

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Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial

14 June 2018

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L-ornithine-L-aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure.

14 June 2018

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Maximal Rates of Excretion and Synthesis of Urea in Normal and Cirrhotic Subjects

14 June 2018

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Ammonia metabolism in chronic obstructive pulmonary disease with special reference to congestive right ventricular failure

14 June 2018

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The dynamics of ammonia metabolism in man. Effects of liver disease and hyperammonemia

14 June 2018

1 reference

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Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444955

Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444955

Clinical and prognostic role of ammonia in advanced decompensated heart failure. The cardio-abdominal syndrome?

14 August 2018

1 reference

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Muscle depletion increases the risk of overt and minimal hepatic encephalopathy: results of a prospective study.

14 August 2018

1 reference

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Ammonia reduction with ornithine phenylacetate restores brain eNOS activity via the DDAH-ADMA pathway in bile duct-ligated cirrhotic rats.

14 August 2018

1 reference

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Backflux of ammonia from brain to blood in human subjects with and without hepatic encephalopathy.

14 August 2018

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Altered expression of genes regulating skeletal muscle mass in the portacaval anastomosis rat.

14 August 2018

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Skeletal muscle atrophy is associated with an increased expression of myostatin and impaired satellite cell function in the portacaval anastamosis rat.

14 August 2018

1 reference

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Effect of ammonia on in vitro diaphragmatic contractility, fatigue and recovery.

14 August 2018

1 reference

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Severe muscle depletion in patients on the liver transplant wait list: Its prevalence and independent prognostic value

14 August 2018

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Crossref

https://api.crossref.org/works/10.1002%2FHEP.29107

Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FHEP.29107

Muscle nitrogen metabolism in chronic hepatic insufficiency

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FHEP.29107

Effect of liver disease and transplantation on urea synthesis in humans: relationship to acid-base status

21 January 2018

1 reference

12 December 2020

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats

1 reference

12 December 2020

The dysfunction of ammonia in heart failure increases with an increase in the intensity of resistance exercise, even with the use of appropriate drug therapy

1 reference

12 December 2020

Ammonia and glutamine metabolism in human liver slices: new aspects on the pathogenesis of hyperammonaemia in chronic liver disease

1 reference

12 December 2020

Treatment of cirrhotic rats with L-ornithine-L-aspartate enhances urea synthesis and lowers serum ammonia levels

1 reference

12 December 2020

Effect of hyperammonemia on leucine and protein metabolism in rats

1 reference

12 December 2020

PLASMA-AMMONIUM LEVELS IN CONGESTIVE CARDIAC FAILURE

1 reference

12 December 2020

Identifiers

DOI

10.1002/HEP.29107

1 reference

10 June 2018

PMCID

5444955

1 reference

10 June 2018

PubMed ID

28195332

1 reference

10 June 2018