TAR cloning and integrated overexpression of 6-demethylchlortetracycline biosynthetic gene cluster in Streptomyces aureofaciens. (Q51170204)

31 March 2018

title

TAR cloning and integrated overexpression of 6-demethylchlortetracycline biosynthetic gene cluster in Streptomyces aureofaciens. (English)

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31 March 2018

Kitasatospora aureofaciens

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1 reference

inferred from

reverse claim

Streptomyces aureofaciens

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inferred from

reverse claim

(2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

1 reference

inferred from

reverse claim

(4S,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,11,12a-pentahydroxy-1,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboximidic acid

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Naxin Wu

1

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31 March 2018

He Huang

series ordinal

2

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31 March 2018

Taoling Min

series ordinal

3

1 reference

31 March 2018

Haifeng Hu

series ordinal

4

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31 March 2018

publication date

26 October 2017

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31 March 2018

full work available at URL

https://academic.oup.com/abbs/article-pdf/49/12/1129/22304113/gmx110.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1093/abbs/gmx110?email=unpaywall_01@example.com

published in

Acta Biochimica et Biophysica Sinica

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31 March 2018

volume

49

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31 March 2018

issue

12

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31 March 2018

page(s)

1129-1134

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31 March 2018

https://api.unpaywall.org/v2/10.1093/abbs/gmx110?email=unpaywall_01@example.com

1 reference

19 March 2024

access restriction status

open access

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based on heuristic

inferred from online access status

cites work

Mechanism of the incidental production of a melanin-like pigment during 6-demethylchlortetracycline production in Streptomyces aureofaciens.

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Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11

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ZouA, a putative relaxase, is essential for dna amplification in Streptomyces kanamyceticus

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A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor

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Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production

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Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

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Direct cloning, genetic engineering, and heterologous expression of the syringolin biosynthetic gene cluster in E. coli through Red/ET recombineering.

21 January 2018

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Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

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Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

21 January 2018

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Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

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Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

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Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

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Metabolic engineering of beta-lactam production

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Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum

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Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus

21 January 2018

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Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus

21 January 2018

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Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization

21 January 2018

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A self-defense gene homologous to tetracycline effluxing gene essential for antibiotic production in Streptomyces aureofaciens.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/ABBS/GMX110

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31 March 2018

PubMed ID

29087452

1 reference

31 March 2018