Mig-6 Mouse Model of Endometrial Cancer. (Q51290637)

2 April 2018

title

Mig-6 Mouse Model of Endometrial Cancer. (English)

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2 April 2018

Jung-Yoon Yoo

2

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author name string

Tae Hoon Kim

series ordinal

1

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2 April 2018

Jae-Wook Jeong

series ordinal

3

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2 April 2018

language of work or name

English

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publication date

1 January 2017

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2 April 2018

Advances in Experimental Medicine and Biology

published in

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2 April 2018

volume

943

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2 April 2018

page(s)

243-259

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2 April 2018

Progesterone regulation of reproductive function through functionally distinct progesterone receptor isoforms

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Progestin regulation of cellular proliferation

21 January 2018

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Reproductive functions of progesterone receptors.

21 January 2018

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Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer.

21 January 2018

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Endometrial adenocarcinoma in young patients: evaluation and fertility-preserving treatment

21 January 2018

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Conservative treatment with progestin and pregnancy outcomes in endometrial cancer.

21 January 2018

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Progesterone: the ultimate endometrial tumor suppressor.

21 January 2018

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Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women

21 January 2018

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Hormonal therapy for the management of grade 1 endometrial adenocarcinoma: a literature review.

21 January 2018

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Role of progesterone in endometrial cancer

21 January 2018

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Conservative therapy for adenocarcinoma and atypical endometrial hyperplasia of the endometrium in young women: central pathologic review and treatment outcome

21 January 2018

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Mechanisms of endometrial progesterone resistance

21 January 2018

1 reference

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Progesterone receptor isoform A but not B is expressed in endometriosis

21 January 2018

1 reference

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Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Identification of a novel mitogen-inducible gene (mig-6): regulation during G1 progression and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.

21 January 2018

1 reference

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Generation of a Mig-6 conditional null allele.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre

21 January 2018

1 reference

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Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia

21 January 2018

1 reference

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Induction of the SAPK activator MIG-6 by the alkylating agent methyl methanesulfonate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig-6, signal transduction, stress response and cancer

21 January 2018

1 reference

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

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Evolutionary expansion of CRIB-containing Cdc42 effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Feedback inhibition by RALT controls signal output by the ErbB network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig-6 is a negative regulator of the epidermal growth factor receptor signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling

21 January 2018

1 reference

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Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer

21 January 2018

1 reference

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Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma

21 January 2018

1 reference

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Mig-6 controls EGFR trafficking and suppresses gliomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

21 January 2018

1 reference

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Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Low expression of Mig-6 is associated with poor survival outcome in NSCLC and inhibits cell apoptosis via ERK-mediated upregulation of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Evidence that MIG-6 is a tumor-suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Epithelial-stromal interaction and progesterone receptors in the mouse uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Blastocyst's state of activity determines the "window" of implantation in the receptive mouse uterus

21 January 2018

1 reference

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21 January 2018

Cancer statistics, 2006

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mammalian reproductive tract mucins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

21 January 2018

Endometrial Carcinoma

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Increased Risk of Endometrial Carcinoma among Users of Conjugated Estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Effect of peritoneal fluid from endometriosis patients on endometrial stromal cell proliferation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Cre-mediated recombination in cell lineages that express the progesterone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Endometrial hyperplasia: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Adjuvant chemotherapy for advanced endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Endometriosis: the host response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Progestin alone as primary treatment of endometrial carcinoma in premenopausal women. Report of seven cases and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Assisted reproductive technologies in conjunction with conservatively treated endometrial adenocarcinoma. A case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Endometrial carcinoma remaining after term pregnancy following conservative treatment with medroxyprogesterone acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Prediction of regression and relapse of endometrial hyperplasia with conservative therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Conservative treatment of early endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Stromal-to-epithelial transition during postpartum endometrial regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Prognostic significance of Notch signalling molecules and their involvement in the invasiveness of endometrial carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Progesterone receptor-B induction of BIRC3 protects endometrial cancer cells from AP1-59-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Signal transducer and activator of transcription 3 is expressed in the decidualized mesometrium of pregnancy and associates with the progesterone receptor through protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Signal transducer and activator of transcription-3 (Stat3) plays a critical role in implantation via progesterone receptor in uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Differential uterine expression of estrogen and progesterone receptors correlates with uterine preparation for implantation and decidualization in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Role of stromal-epithelial interactions in hormonal responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

New medical treatments for endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Genomic sequence analysis of the mouse Naip gene array

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Leukemia inhibitory factor induces an antiapoptotic response in oligodendrocytes through Akt-phosphorylation and up-regulation of 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Signaling regulation of genomic and nongenomic functions of estrogen receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

17beta-estradiol signaling in skeletal muscle cells and its relationship to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Combined Estrogen and Progesterone Use and Endometrial Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Fertility-preserving treatment with progestin, and pathological criteria to predict responses, in young women with endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Hypertrophy and hyperplasia in the mouse uterus after oestrogen treatment: an autoradiographic study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Cell type-specific localization of c-myc protein in the mouse uterus: modulation by steroid hormones and analysis of the periimplantation period

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

The inhibition by progesterone of uterine epithelial proliferation in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Mutational Analysis of thePTENGene in Endometrial Carcinoma and Hyperplasia

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Progestin treatment of atypical hyperplasia and well-differentiated carcinoma of the endometrium in women under age 40

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Estrogen and progesterone receptors in endometrial cancer and their prognostic relevance

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

Steroid receptors and clinical outcome in patients with adenocarcinoma of the endometrium

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-43139-0_8

10.1007/978-3-319-43139-0_8

31 March 2020

Identifiers

DOI

1 reference

2 April 2018

PubMed ID

27910070

1 reference

2 April 2018