Gene amplification and its application in cell and tissue engineering. (Q51335780)

3 April 2018

title

Gene amplification and its application in cell and tissue engineering. (English)

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3 April 2018

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1

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3 April 2018

publication date

1 January 2002

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3 April 2018

Journal of Bioscience and Bioengineering

published in

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3 April 2018

volume

94

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3 April 2018

issue

6

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3 April 2018

page(s)

600-605

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3 April 2018

Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA.

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Gene amplification in the lac region of E. coli

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Prevention of toxicity of amethopterin for sarcoma-180 cells in tissue culture

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On the nature of hereditable variation in cultured somatic cells

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7 January 2021

Mutations and epimutations in mammalian cells

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7 January 2021

Gene amplification in mammalian cells: strategies for protein production

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7 January 2021

Selective retension of active cells employing low centrifugal force at the medium change during suspension culture of Chinese hamster ovary cells producing tPA.

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Aggregate formation of rCHO cells and its maintenance in repeated batch culture in the absence of cell adhesion materials.

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7 January 2021

Selection and coamplification of heterologous genes in mammalian cells

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7 January 2021

Expression and amplification of engineered mouse dihydrofolate reductase minigenes

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7 January 2021

Amplified expression constructs for human tissue-type plasminogen activator in Chinese hamster ovary cells: instability in the absence of selective pressure

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7 January 2021

Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage

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7 January 2021

Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events

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7 January 2021

Chromosomal destabilization during gene amplification

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7 January 2021

Chromosomal fragile sites and DNA amplification in drug-resistant cells

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7 January 2021

Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

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7 January 2021

Gene amplification; what are we learning?

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Flow cytometry: an improved method for the selection of highly productive gene-amplified CHO cells using flow cytometry.

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7 January 2021

Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes

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7 January 2021

Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes.

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7 January 2021

Secretion capture and report web: use of affinity derivatized agarose microdroplets for the selection of hybridoma cells

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Improved cell line development by a high throughput affinity capture surface display technique to select for high secretors

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7 January 2021

Selection of highly productive mammalian cells based on an inducible growth advantage using an antibody/receptor chimera.

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7 January 2021

An attempt to add biological functions by genetic engineering in order to produce high-performance bioreactor cells for hybrid artificial liver: transfection of glutamine synthetase into Chinese hamster ovary (CHO) cell

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7 January 2021

Adaptive amplification: an inducible chromosomal instability mechanism.

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7 January 2021

10.1016/S1389-1723(02)80201-8

Identifiers

DOI

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3 April 2018

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3 April 2018