Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers. (Q51487611)

5 April 2018

title

Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers. (English)

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5 April 2018

author name string

Tomasz Zaremba

1

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Huw D Thomas

2

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Michael Cole

3

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Sally A Coulthard

4

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Elizabeth R Plummer

5

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Nicola J Curtin

6

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language of work or name

English

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publication date

1 June 2011

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5 April 2018

published in

Biochemical Journal

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volume

436

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issue

3

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page(s)

671-679

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5 April 2018

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

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The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme function

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Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1.

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Transcription factor Yin Yang 1 stimulates poly(ADP-ribosyl)ation and DNA repair

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Association between polymorphisms in DNA base excision repair genes XRCC1, APE1, and ADPRT and differentiated thyroid carcinoma

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Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

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Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors.

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Oral poly(ADP-ribose) polymerase-1 inhibitor BSI-401 has antitumor activity and synergizes with oxaliplatin against pancreatic cancer, preventing acute neurotoxicity

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Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines

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New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity

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Genetic sequence variations and ADPRT haplotype analysis in French Canadian families with high risk of breast cancer

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Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.

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Novel modulators of poly(ADP-ribose) polymerase

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Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke

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Poly (ADP-ribose) polymerase-1 initiated neuronal cell death pathway--do androgens matter?

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Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

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A prospective study on lung toxicity in patients treated with gemcitabine and carboplatin: clinical, radiological and functional assessment.

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A poly(ADP-ribose) polymerase haplotype spanning the promoter region confers susceptibility to rheumatoid arthritis

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Identifiers

DOI

10.1042/BJ20101723

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5 April 2018

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5 April 2018