Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys. (Q51496187)

5 April 2018

title

Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys. (English)

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5 April 2018

author name string

C Jerome

series ordinal

1

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5 April 2018

M Missbach

series ordinal

2

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5 April 2018

R Gamse

series ordinal

3

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5 April 2018

language of work or name

English

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publication date

5 March 2011

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5 April 2018

Osteoporosis International

published in

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5 April 2018

volume

23

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5 April 2018

issue

1

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5 April 2018

page(s)

339-349

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5 April 2018

https://scigraph.springernature.com/pub.10.1007/s00198-011-1593-2

exact match

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cites work

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Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

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Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate

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A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys.

21 January 2018

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Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys

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10.1007/S00198-011-1593-2

Identifiers

DOI

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5 April 2018

PubMed ID

21380636

1 reference

5 April 2018