Developmental immunotoxicology (DIT): windows of vulnerability, immune dysfunction and safety assessment. (Q51662537)

9 April 2018

title

Developmental immunotoxicology (DIT): windows of vulnerability, immune dysfunction and safety assessment. (English)

1 reference

9 April 2018

1 reference

Rodney R Dietert

1

1 reference

9 April 2018

publication date

1 October 2008

1 reference

9 April 2018

Journal of Immunotoxicology

published in

1 reference

9 April 2018

volume

5

1 reference

9 April 2018

issue

4

1 reference

9 April 2018

page(s)

401-412

1 reference

9 April 2018

Long-term alteration of adult bone marrow colony formation by prenatal chlordane exposure

cites work

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Diethylstilbestrol (DES)-induced fetal thymic atrophy in C57BL/6 mice: inhibited thymocyte differentiation and increased apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Gender-specific effects of prenatal chlordane exposure on myeloid cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Exposure to lead during critical windows of embryonic development: differential immunotoxic outcome based on stage of exposure and gender

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

What's so special about the developing immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Impaired allogeneic activation and T-helper 1 differentiation of human cord blood naive CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Inflammatory bowel disease: the role of environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Lupus and pregnancy: complex yet manageable

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Workshop to identify critical windows of exposure for children's health: immune and respiratory systems work group summary

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental immunotoxicity testing and protection of children's health

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Early-life immune insult and developmental immunotoxicity (DIT)-associated diseases: potential of herbal- and fungal-derived medicinals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Methodologies for developmental immunotoxicity (DIT) testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Perinatal immunotoxicity: why adult exposure assessment fails to predict risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental immunotoxicology: emerging issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental immunotoxicity of dexamethasone: comparison of fetal versus adult exposures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Possible role for early-life immune insult including developmental immunotoxicity in chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

The managed immune system: protecting the womb to delay the tomb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Embryonic exposure to aflatoxin-B1: mutagenicity and influence on development and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Th2 immune deviation induced by pregnancy: the two faces of autoimmune rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin (IL)-4 And IL-10 gene transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Diethylstilbestrol exposure during fetal development affects thymus: studies in fourteen-month-old mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

2,3,7,8-tetrachlorodibenzo-p-dioxin enhances negative selection of T cells in the thymus but allows autoreactive T cells to escape deletion and migrate to the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Lead effects on development and function of bone marrow-derived dendritic cells promote Th2 immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Environmental tobacco smoke and the epidemic of asthma in children: the role of cigarette use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Modulation of immune response following dietary genistein exposure in F0 and F1 generations of C57BL/6 mice: evidence of thymic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Time trends in allergic disorders in the UK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Exposure of pregnant mice to an air pollutant aerosol increases asthma susceptibility in offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Prenatal immunotoxicant exposure and postnatal autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Fetal hematopoietic alterations after maternal exposure to benzo[a]pyrene: a cytometric evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Alterations in Murine Fetal Thymus and Liver Hematopoietic Cell Populations Following Developmental Exposure to 7,12-Dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Fetal thymic atrophy after exposure to T-2 toxin: selectivity for lymphoid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

A proposed testing framework for developmental immunotoxicology (DIT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Symposium summary: children's health risk - what's so special about the developing immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Evidence of a TH 1 type response associated with recurrent miscarriage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Nonylphenol alters the activity of splenic NK cells and the numbers of leukocyte subpopulations in Sprague-Dawley rats: a two-generation feeding study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Gestational exposure to perfluorooctane sulfonate suppresses immune function in B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Efficient maturation and cytokine production of neonatal DCs requires combined proinflammatory signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental toxicology evaluations--issues with including neurotoxicology and immunotoxicology assessments in reproductive toxicology studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Critical windows in development of the rodent immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Maternal alcohol ingestion reduces surfactant protein A expression by preterm fetal lung epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental windows of differential lead-induced immunotoxicity in chickens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Innate immunity of the newborn: basic mechanisms and clinical correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immune system maturity and sensitivity to chemical exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

The comparative immunotoxicity of five selected compounds following developmental or adult exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Soluble CD14 and CD83 from human neonatal antigen-presenting cells are inducible by commensal bacteria and suppress allergen-induced human neonatal Th2 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Biomarkers to assess potential developmental immunotoxicity in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Dexamethasone selectively inhibits differentiation of cord blood stem cell derived-dendritic cell (DC) precursors into immature DCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Possible early prediction of preterm birth by determination of novel proinflammatory factors in midtrimester amniotic fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

NF-kappaB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunological stress at the maternal-foetal interface: a link between neurodevelopment and adult psychopathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Effects of nicotine exposure on T cell development in fetal thymus organ culture: arrest of T cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Effects of prenatal exposure to cigarette smoke on offspring tumor susceptibility and associated immune mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Selection of probiotic bacteria for prevention of allergic diseases: immunomodulation of neonatal dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Transmaternal exposure to bisphenol a modulates the development of oral tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

The remission of rheumatoid arthritis during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Suppression of glial activation is involved in the protection of IL-10 on maternal E. coli induced neonatal white matter injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Developmental immunotoxicity of trichloroethylene (TCE): studies in B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

In utero exposure to environmental tobacco smoke potentiates adult responses to allergen in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

T cells in normal pregnancy and recurrent pregnancy loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Sex-specific effects of neonatal exposures to low levels of cadmium through maternal milk on development and immune functions of juvenile and adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

In vivo dysfunction of the term alveolar macrophage after in utero ethanol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunology of pregnancy. Implications for the mother

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Maternal adrenalectomy alters the immune and endocrine functions of fetal alcohol-exposed male offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Maternal exposure to benzo[a]pyrene alters development of T lymphocytes in offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunomodulation by cocaine and ketamine in postnatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immaturity of infection control in preterm and term newborns is associated with impaired toll-like receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Regulatory T cells and regulatory natural killer (NK) cells play important roles in feto-maternal tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Dysregulation of expression of immunoregulatory and cytokine genes and its association with the immaturity in neonatal phagocytic and cellular immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Anti-ulcer treatment during pregnancy induces food allergy in mouse mothers and a Th2-bias in their offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunotoxicity: the risk is real

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Assessing the health effects and risks associated with children's inhalation exposures--asthma and allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Prenatal HgCl2 exposure in BALB/c mice: gender-specific effects on the ontogeny of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Oral (gavage), in utero and post-natal exposure of Sprague-Dawley rats to low doses of tributyltin chloride. Part II: effects on the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Development of interleukin-12-producing capacity throughout childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Defective antigen-presenting cell function in human neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

A dose-response study of the effects of prenatal and lactational exposure to TCDD on the immune response to influenza a virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Persistent suppression of contact hypersensitivity, and altered T-cell parameters in F344 rats exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Neonatal B cells suppress innate toll-like receptor immune responses and modulate alloimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Detrimental effects of tobacco smoke exposure during development on postnatal lung function and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Effects of intrauterine inflammation on the developing mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F0 and F1 generations of Sprague Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Abnormal cytokine levels in non-pregnant women with a history of recurrent miscarriage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

A brief targeted review of susceptibility factors, environmental exposures, asthma incidence, and recommendations for future asthma incidence research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Prenatal exposure to bisphenol A up-regulates immune responses, including T helper 1 and T helper 2 responses, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Immunology of pregnancy: cellular mechanisms allowing fetal survival within the maternal uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Maternal Tobacco Smoking and Decreased Leukocytes, Including Dendritic Cells, in Neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

Blockade of CD86 signaling facilitates a Th2 bias at the maternal-fetal interface and expands peripheral CD4+CD25+ regulatory T cells to rescue abortion-prone fetuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15476910802483324

10.1080/15476910802483324

21 January 2018

Identifiers

DOI

1 reference

9 April 2018

1 reference

9 April 2018