GFP-tagged CFTR transgene is functional in the G551D cystic fibrosis mouse colon. (Q51666570)

9 April 2018

title

GFP-tagged CFTR transgene is functional in the G551D cystic fibrosis mouse colon. (English)

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9 April 2018

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9 April 2018

Karl Kunzelmann

5

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9 April 2018

author name string

B McMorran

2

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9 April 2018

R Schreiber

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B J Wainwright

4

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9 April 2018

publication date

1 April 2003

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9 April 2018

number of pages

9

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Journal of Membrane Biology

inferred from page(s)

published in

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9 April 2018

volume

192

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9 April 2018

issue

3

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page(s)

159-167

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9 April 2018

Electrolyte transport in the mammalian colon: mechanisms and implications for disease

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Green fluorescent protein (GFP) fusion constructs in gene therapy research

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Ion transport abnormalities in rectal suction biopsies from children with cystic fibrosis

21 January 2018

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Cystic fibrosis patients bearing both the common missense mutation Gly----Asp at codon 551 and the delta F508 mutation are clinically indistinguishable from delta F508 homozygotes, except for decreased risk of meconium ileus

21 January 2018

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Cholinergic ion secretion in human colon requires coactivation by cAMP

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Ca2+ activation of hSlo K+ channel is suppressed by N-terminal GFP tag.

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Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors

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Functional expression of GFP-tagged Kv1.3 and Kv1.4 channels in HEK 293 cells

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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Hyperabsorption of Na+ and raised Ca(2+)-mediated Cl- secretion in nasal epithelia of CF mice.

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CFTR-mediated inhibition of epithelial Na+ conductance in human colon is defective in cystic fibrosis

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Intestinal physiology and pathology in gene-targeted mouse models of cystic fibrosis

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The cystic fibrosis transmembrane conductance regulator and its function in epithelial transport

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Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

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Gene complementation of airway epithelium in the cystic fibrosis mouse is necessary and sufficient to correct the pathogen clearance and inflammatory abnormalities

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Functional expression of a GFP-tagged Kv1.5 alpha-subunit in mouse ventricle

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Impact of heterogeneity within cultured cells on bacterial invasion: analysis of Pseudomonas aeruginosa and Salmonella enterica serovar typhi entry into MDCK cells by using a green fluorescent protein-labelled cystic fibrosis transmembrane conductan

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Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

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High-efficiency transfer of cystic fibrosis transmembrane conductance regulator cDNA into cystic fibrosis airway cells in culture using lactosylated polylysine as a vector.

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Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

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Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis

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Chloride channels in the luminal membrane of rat pancreatic acini

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A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

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Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer

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A PDZ-interacting domain in CFTR is an apical membrane polarization signal

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Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

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Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

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Distribution of ion transport mRNAs throughout murine nose and lung

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Pathophysiology of gene-targeted mouse models for cystic fibrosis

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Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung.

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Defective cholinergic Cl(-) secretion and detection of K(+) secretion in rectal biopsies from cystic fibrosis patients

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Targeting transgene expression to airway epithelia and submucosal glands, prominent sites of human CFTR expression

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CFTR as a cAMP-dependent regulator of sodium channels

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Gene transfer for cystic fibrosis

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A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins

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Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in madin-darby canine kidney cells

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CFTR is a conductance regulator as well as a chloride channel

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Green fluorescent protein-based halide indicators with improved chloride and iodide affinities

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Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds

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The CF salt controversy: in vivo observations and therapeutic approaches.

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Determinants of mild clinical symptoms in cystic fibrosis patients. Residual chloride secretion measured in rectal biopsies in relation to the genotype

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Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlations.

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12 December 2020

10.1007/S00232-002-1072-Y

Identifiers

DOI

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9 April 2018

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9 April 2018