Influence of CYP2C9 and VKORC1 polymorphisms on warfarin and acenocoumarol in a sample of Lebanese people. (Q51739644)

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18 January 2020

title

Influence of CYP2C9 and VKORC1 polymorphisms on warfarin and acenocoumarol in a sample of Lebanese people (English)

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18 January 2020

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9

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18 January 2020

Mohammad Zouheir Habbal

3

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author name string

Maria O Esmerian

1

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18 January 2020

Zahi Mitri

2

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18 January 2020

Eddy Geryess

4

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18 January 2020

Ghazi Zaatari

5

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18 January 2020

Samir Alam

6

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18 January 2020

Hadi N Skouri

7

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Rami A Mahfouz

8

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Nathalie K Zgheib

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publication date

8 December 2010

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The Journal of Clinical Pharmacology

18 January 2020

published in

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volume

51

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issue

10

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page(s)

1418-1428

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Hormonal effects on drug metabolism through the CYP system: perspectives on their potential significance in the era of pharmacogenomics

18 January 2020

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Effects of CYP2C9 and VKORC1 on INR variations and dose requirements during initial phase of anticoagulant therapy

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A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data

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Acenocoumarol pharmacokinetics in relation to cytochrome P450 2C9 genotype

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Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients

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Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives

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Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population

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Validation of a method for the determination of (R)-warfarin and (S)-warfarin in human plasma using LC with UV detection

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Determination of warfarin enantiomers and hydroxylated metabolites in human blood plasma by liquid chromatography with achiral and chiral separation

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CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: a prospective randomized controlled study.

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CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy

21 January 2018

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VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients.

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Contribution of CYP2C9 to variability in vitamin K antagonist metabolism

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Acenocoumarol stabilization is delayed in CYP2C93 carriers

21 January 2018

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The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

21 January 2018

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VKORC1: molecular target of coumarins

21 January 2018

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Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity.

21 January 2018

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VKORC1 and CYP2C9 genotypes and acenocoumarol anticoagulation status: interaction between both genotypes affects overanticoagulation.

21 January 2018

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

21 January 2018

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Identifiers

DOI

10.1177/0091270010382910

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21148049%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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