Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. (Q51746101)

11 April 2018

title

Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. (English)

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11 April 2018

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6

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Josef S Smolen

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object named as

Josef S Smolen

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Nikolaus B Binder

1

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Birgit Niederreiter

2

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Oskar Hoffmann

3

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Richard Stange

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Thomas Pap

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Matthias Mack

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Reinhold G Erben

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Kurt Redlich

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language of work or name

English

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publication date

29 March 2009

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11 April 2018

published in

Nature Medicine

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11 April 2018

volume

15

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11 April 2018

issue

4

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11 April 2018

page(s)

417-424

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Bone resorption by osteoclasts

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Evaluation of serum osteocalcin as an index of altered bone metabolism

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Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice

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A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population.

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Estrogen decreases expression of chemokine receptors, and suppresses chemokine bioactivity in murine monocytes

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The expression of CCL2 by T lymphocytes of mammary tumor bearers: role of tumor-derived factors

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Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats

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Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis

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Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts

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Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis.

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MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

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Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1.

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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MCP-1-induced human osteoclast-like cells are tartrate-resistant acid phosphatase, NFATc1, and calcitonin receptor-positive but require receptor activator of NFkappaB ligand for bone resorption

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Regulation of monocyte chemotactic protein-1 expression in human endometrial stromal cells by estrogen and progesterone

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Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails

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CD44 is a determinant of inflammatory bone loss

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Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

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Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

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Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

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Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice

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Differentiation and function of osteoclasts

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RANK is essential for osteoclast and lymph node development

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Direct and indirect estrogen actions on osteoblasts and osteoclasts

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Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.

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Denosumab in postmenopausal women with low bone mineral density

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Sex steroids and bone

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Role of cytokines in bone resorption

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Biochemical markers of bone turnover in Paget's disease

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Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha

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Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral density

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

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Induction of chemokines and chemokine receptors CCR2b and CCR4 in authentic human osteoclasts differentiated with RANKL and osteoclast like cells differentiated by MCP-1 and RANTES.

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Cytokines, hematopoiesis, osteoclastogenesis, and estrogens

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SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

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Estrogen deficiency and bone loss: an inflammatory tale

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Effect of hormone replacement therapy on nitric oxide bioactivity and monocyte chemoattractant protein-1 levels

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CCL9/MIP-1gamma and its receptor CCR1 are the major chemokine ligand/receptor species expressed by osteoclasts

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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors

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12 December 2020

Identifiers

DOI

10.1038/NM.1945

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11 April 2018

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11 April 2018