Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay. (Q51749302)

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10 March 2020

title

Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay (English)

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10 March 2020

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5

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10 March 2020

Nils Cordes

6

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10 March 2020

Michael Baumann

7

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10 March 2020

10

L A Kunz-Schughart

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10 March 2020

author name string

M Ingargiola

1

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10 March 2020

R Runge

2

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10 March 2020

J-M Heldt

3

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10 March 2020

R Freudenberg

4

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10 March 2020

J Kotzerke

8

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G Brockhoff

9

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language of work or name

English

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publication date

11 February 2014

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International Journal of Cancer

10 March 2020

number of pages

13

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based on heuristic

inferred from page(s)

published in

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volume

135

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issue

4

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page(s)

968-980

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Clinical radioimmunotherapy--the role of radiobiology.

10 March 2020

cites work

1 reference

Cancer radioimmunotherapy

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1 reference

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The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells

21 January 2018

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Untangling the ErbB signalling network

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EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells

21 January 2018

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Combination of cetuximab with chemoradiation, trastuzumab or MAPK inhibitors: mechanisms of sensitisation of cervical cancer cells

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Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression

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Different classes of EGFR inhibitors may have different potential to improve local tumour control after fractionated irradiation: a study on C225 in FaDu hSCC.

21 January 2018

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Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification

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Rapid re-expression of CD133 protein in colorectal cancer cell lines in vitro and in vivo

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Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation.

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Selecting fluorochrome conjugates for maximum sensitivity

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Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase

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Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654

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Proteomics of the radioresistant phenotype in head-and-neck cancer: Gp96 as a novel prediction marker and sensitizing target for radiotherapy.

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Radioactive EGFR antibody cetuximab in multimodal cancer treatment: stability and synergistic effects with radiotherapy

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Exploring the role of cancer stem cells in radioresistance

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Penetration and binding of monoclonal antibody in human osteosarcoma multicell spheroids. Comparison of confocal laser scanning microscopy and autoradiography

21 January 2018

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A novel mechanism for anti-EGFR antibody action involves chemokine-mediated leukocyte infiltration

21 January 2018

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The selection of antibodies for targeted therapy of small-cell lung cancer (SCLC) using a human tumour spheroid model to compare the uptake of cluster 1 and cluster w4 antibodies

21 January 2018

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The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors

21 January 2018

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Effects of charge on antibody tissue distribution and pharmacokinetics.

21 January 2018

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Effects of 131I-labeled TNT-1 radioimmunotherapy on HT-29 human colon adenocarcinoma spheroids

21 January 2018

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Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule

21 January 2018

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Endocytosis and intracellular trafficking of ErbBs

21 January 2018

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21 years of biologically effective dose

21 January 2018

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Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

21 January 2018

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Yttrium-labelled peptides for therapy of NET.

21 January 2018

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Influence of the linker on the biodistribution and catabolism of actinium-225 self-immolative tumor-targeted isotope generators

21 January 2018

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Preclinical and clinical safety of monoclonal antibodies

21 January 2018

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Engineering functional epithelium for regenerative medicine and in vitro organ models: a review.

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Skin tissue engineering--in vivo and in vitro applications

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Population pharmacokinetics of cetuximab in patients with squamous cell carcinoma of the head and neck.

21 January 2018

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Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized Controlled Trial

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24615356%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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