Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. (Q51795776)

12 April 2018

title

Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. (English)

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12 April 2018

author name string

Dianne Botta

1

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12 April 2018

Shengli Shi

2

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12 April 2018

Collin C White

3

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12 April 2018

Michael J Dabrowski

4

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12 April 2018

Cassie L Keener

5

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Sengkeo L Srinouanprachanh

6

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12 April 2018

Federico M Farin

7

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12 April 2018

Carol B Ware

8

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12 April 2018

Warren C Ladiges

9

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12 April 2018

Robert H Pierce

10

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12 April 2018

Nelson Fausto

11

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12 April 2018

Terrance J Kavanagh

12

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12 April 2018

language of work or name

English

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publication date

13 July 2006

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12 April 2018

Journal of Biological Chemistry

published in

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volume

281

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issue

39

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12 April 2018

page(s)

28865-28875

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https://api.crossref.org/works/10.1074%2FJBC.M605143200

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Mechanisms of hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605143200

Concise review of the glutathione S-transferases and their significance to toxicology

21 January 2018

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Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase

21 January 2018

1 reference

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Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure

21 January 2018

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Molecular mechanisms of the hepatotoxicity caused by acetaminophen

21 January 2018

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Acetaminophen-induced hepatotoxicity

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Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

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Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition

21 January 2018

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N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

21 January 2018

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Biologic and pharmacologic regulation of mammalian glutathione synthesis

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Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz

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Molecular cloning and sequencing of the cDNA encoding the catalytic subunit of mouse glutamate-cysteine ligase

21 January 2018

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Molecular cloning and sequencing of the cDNA encoding mouse glutamate-cysteine ligase regulatory subunit

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A regulatory system for use in gene transfer

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Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death

21 January 2018

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TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms

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Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis

21 January 2018

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Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity

21 January 2018

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Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

21 January 2018

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Acetaminophen metabolism does not contribute to gender difference in its hepatotoxicity in mouse.

21 January 2018

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Early hepatic microvascular injury in response to acetaminophen toxicity

21 January 2018

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Effects of acetaminophen on hepatic microcirculation in mice

21 January 2018

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Glutathione: toxicological implications

21 January 2018

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The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity

21 January 2018

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Hydrogen peroxide increases the activity of gamma-glutamylcysteine synthetase in cultured Chinese hamster V79 cells

21 January 2018

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Arsenic compound-induced increases in glutathione levels in cultured Chinese hamster V79 cells and mechanisms associated with changes in gamma-glutamylcysteine synthetase activity, cystine uptake and utilization of cysteine

21 January 2018

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Human glutamate cysteine ligase gene regulation through the electrophile response element

21 January 2018

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Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity

21 January 2018

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Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

21 January 2018

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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

21 January 2018

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Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation

21 January 2018

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Immunochemical analysis of acetaminophen covalent binding to proteins. Partial characterization of the major acetaminophen-binding liver proteins

21 January 2018

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Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

21 January 2018

1 reference

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Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress

21 January 2018

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Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice

21 January 2018

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Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice

21 January 2018

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Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress

21 January 2018

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Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione

21 January 2018

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Scavenging peroxynitrite with glutathione promotes regeneration and enhances survival during acetaminophen-induced liver injury in mice

21 January 2018

1 reference

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Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

21 January 2018

1 reference

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Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function

21 January 2018

1 reference

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Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M605143200

1 reference

12 April 2018

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12 April 2018