Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336. (Q51807087)

12 April 2018

title

Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336. (English)

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Waldemar Gonsiorek

1

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David Hesk

2

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Shu-Cheng Chen

3

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David Kinsley

4

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Jay S Fine

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James V Jackson

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Loretta A Bober

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Gregory Deno

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Hong Bian

9

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James Fossetta

10

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Charles A Lunn

11

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Joseph A Kozlowski

12

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Brian Lavey

13

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John Piwinski

14

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Satwant K Narula

15

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Daniel J Lundell

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R William Hipkin

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language of work or name

English

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publication date

5 June 2006

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Journal of Biological Chemistry

published in

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volume

281

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issue

38

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page(s)

28143-28151

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2-Arachidonoylglycerol Induces the Migration of HL-60 Cells Differentiated into Macrophage-like Cells and Human Peripheral Blood Monocytes through the Cannabinoid CB2 Receptor-dependent Mechanism

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2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils

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The endogenous cannabinoid 2-arachidonoyl glycerol as in vivo chemoattractant for dendritic cells and adjuvant for Th1 response to a soluble protein

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Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies

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A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo

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Honey stimulates inflammatory cytokine production from monocytes.

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Pharmacological characterization of human S1P4 using a novel radioligand, [4,5-3H]-dihydrosphingosine-1-phosphate

21 January 2018

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Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL-60 cells: antagonism of hCCR1 activation by MIP-1beta

21 January 2018

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Methylene chloride fraction of Spatholobi Caulis induces apoptosis via caspase dependent pathway in U937 cells

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Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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The study of CXCR3 and CCR7 pharmacology using [35S]GTPgammaS exchange assays in cell membranes and permeabilized peripheral blood lymphocytes

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

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The endogenous cannabinoid anandamide is a lipid messenger activating cell growth via a cannabinoid receptor-independent pathway in hematopoietic cell lines

21 January 2018

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Genomic and functional changes induced by the activation of the peripheral cannabinoid receptor CB2 in the promyelocytic cells HL-60. Possible involvement of the CB2 receptor in cell differentiation

21 January 2018

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Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells

21 January 2018

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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease

21 January 2018

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Role of transforming growth factor-βthe preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B

21 January 2018

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Endogenous retroviral superantigen presentation by B cells induces the development of type 1 CD4+ T helper lymphocytes

21 January 2018

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Cannabinoid-receptor expression in human leukocytes

21 January 2018

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Molecular characterization of a peripheral receptor for cannabinoids

21 January 2018

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Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

21 January 2018

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Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

21 January 2018

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Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2.

21 January 2018

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Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system

21 January 2018

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Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells.

21 January 2018

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Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

21 January 2018

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Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia

21 January 2018

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SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

21 January 2018

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Distinct expression profiles of the peripheral cannabinoid receptor in lymphoid tissues depending on receptor activation status

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M602364200

1 reference

12 April 2018

PubMed ID

16754676

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12 April 2018