Localization, topology, and function of the LCB1 subunit of serine palmitoyltransferase in mammalian cells. (Q51841172)

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15 December 2019

title

Localization, topology, and function of the LCB1 subunit of serine palmitoyltransferase in mammalian cells (English)

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15 December 2019

1

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15 December 2019

author name string

Masahiro Nishijima

series ordinal

2

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15 December 2019

Kentaro Hanada

series ordinal

3

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15 December 2019

language of work or name

English

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publication date

2 December 2002

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Journal of Biological Chemistry

15 December 2019

number of pages

8

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based on heuristic

inferred from page(s)

published in

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15 December 2019

volume

278

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15 December 2019

issue

6

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15 December 2019

page(s)

4176-4183

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De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway

15 December 2019

cites work

1 reference

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A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis

21 January 2018

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Mammalian cell mutants resistant to a sphingomyelin-directed cytolysin. Genetic and biochemical evidence for complex formation of the LCB1 protein with the LCB2 protein for serine palmitoyltransferase

21 January 2018

1 reference

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Purification of the serine palmitoyltransferase complex responsible for sphingoid base synthesis by using affinity peptide chromatography techniques

21 January 2018

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Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis

21 January 2018

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SPTLC1 is mutated in hereditary sensory neuropathy, type 1

21 January 2018

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Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I

21 January 2018

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Mutations in the yeast LCB1 and LCB2 genes, including those corresponding to the hereditary sensory neuropathy type I mutations, dominantly inactivate serine palmitoyltransferase

21 January 2018

1 reference

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Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids

21 January 2018

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The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

21 January 2018

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A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction

21 January 2018

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Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes.

21 January 2018

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Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells

21 January 2018

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Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

21 January 2018

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Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains

21 January 2018

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A C-terminal signal prevents secretion of luminal ER proteins

21 January 2018

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Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity

21 January 2018

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The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme

21 January 2018

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Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies

21 January 2018

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A simple method for displaying the hydropathic character of a protein

21 January 2018

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The detection and classification of membrane-spanning proteins.

21 January 2018

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Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method

21 January 2018

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Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209602200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464627%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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