JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats. (Q51895488)

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16 January 2020

title

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats (English)

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16 January 2020

author name string

Ruggero Galici

1

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16 January 2020

Amir H Rezvani

2

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16 January 2020

Leah Aluisio

3

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16 January 2020

Brian Lord

4

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16 January 2020

Ian Fraser

6

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16 January 2020

Jamin Boggs

7

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16 January 2020

Natalie Welty

8

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16 January 2020

S Timothy Motley

10

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16 January 2020

Michael A Letavic

11

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16 January 2020

Nicholas I Carruthers

12

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16 January 2020

Christine Dugovic

13

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16 January 2020

Timothy W Lovenberg

14

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16 January 2020

Pascal Bonaventure

15

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16 January 2020

publication date

18 November 2010

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16 January 2020

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16 January 2020

volume

214

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16 January 2020

issue

4

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16 January 2020

page(s)

829-841

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Distribution and modulation of histamine H(3) receptors in basal ganglia and frontal cortex of healthy controls and patients with Parkinson's disease

16 January 2020

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Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor

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Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents.

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Histamine H(3) receptors depress synaptic transmission in the corticostriatal pathway

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The histamine H3 receptor: an attractive target for the treatment of cognitive disorders

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Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

21 January 2018

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JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition

21 January 2018

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Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]GABA release from depolarization-stimulated slices of rat substantia nigra pars reticulata

21 January 2018

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Neurocircuitry targets in ethanol reward and dependence

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The role of histamine and the tuberomamillary nucleus in the nervous system

21 January 2018

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Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms

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The tuberomammillary nucleus projections in the control of learning, memory and reinforcement processes: evidence for an inhibitory role

21 January 2018

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Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings

21 January 2018

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Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development

21 January 2018

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Low brain histamine content affects ethanol-induced motor impairment

21 January 2018

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Histamine H3 receptor activation inhibits glutamate release from rat striatal synaptosomes

21 January 2018

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Histamine and H3 receptor-dependent mechanisms regulate ethanol stimulation and conditioned place preference in mice

21 January 2018

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Behavioural features of alcohol-preferring rats: focus on inbred strains

21 January 2018

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A detailed mapping of the histamine H(3) receptor and its gene transcripts in rat brain

21 January 2018

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A detailed autoradiographic mapping of histamine H3 receptors in rat brain areas

21 January 2018

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Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.

21 January 2018

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Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats

21 January 2018

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The alcohol-preferring P rat and animal models of excessive alcohol drinking

21 January 2018

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Alcohol addiction research: from animal models to clinics

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Medication development for addictive disorders: the state of the science

21 January 2018

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The tuberomammillary nucleus region as a reinforcement inhibiting substrate: facilitation of ipsihypothalamic self-stimulation by unilateral ibotenic acid lesions

21 January 2018

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Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system

21 January 2018

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Histamine inhibits dopamine release in the mouse striatum via presynaptic H3 receptors

21 January 2018

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12 December 2020

Heterogeneous distributions of histamine H3, dopamine D1 and D2 receptors in rat brain.

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12 December 2020

Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats

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Increased brain histamine in an alcohol-preferring rat line and modulation of ethanol consumption by H(3) receptor mechanisms.

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Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat.

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Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol

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Combination pharmacotherapy: a mixture of small doses of naltrexone, fluoxetine, and a thyrotropin-releasing hormone analogue reduces alcohol intake in three strains of alcohol-preferring rats

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10.1007/S00213-010-2092-4

Identifiers

DOI

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release_acvb2qooznfjllcjntceygysoy

16 January 2020

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Fatcat

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24 November 2022

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