Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures (Q51898200)

17 April 2018

title

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures (English)

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

stem cell differentiation

30 July 2024

main subject

1 reference

based on heuristic

inferred from title

gene expression profiling

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

alternatives to animal testing

30 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

7

Jos C S Kleinjans

1 reference

17 April 2018

Jeroen L Pennings

2

object named as

Jeroen L. A. Pennings

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

author name string

Sandra Claessen

5

1 reference

17 April 2018

Dorien A. M. van Dartel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

Liset J. J. de la Fonteyne

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

Karen J. J. Brauers

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

Joost H. van Delft

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

Jos C. S. Kleinjans

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

Aldert H. Piersma

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

30 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20935163

30 July 2024

publication date

8 October 2010

1 reference

17 April 2018

full work available at URL

https://academic.oup.com/toxsci/article-pdf/119/1/126/10954331/kfq291.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

http://toxsci.oxfordjournals.org/cgi/content/abstract/119/1/126

30 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20935163

http://academic.oup.com/toxsci/article-pdf/119/1/126/10954331/kfq291.pdf

30 July 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

30 July 2024

published in

Toxicological Sciences

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17 April 2018

volume

119

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17 April 2018

issue

1

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17 April 2018

page(s)

126-134

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17 April 2018

describes a project that uses

1 reference

First steps in establishing a developmental toxicity test method based on human embryonic stem cells

1

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Defining a developmental path to neural fate by global expression profiling of mouse embryonic stem cells and adult neural stem/progenitor cells.

30 July 2024

2

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat.

30 July 2024

3

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

The Relative Semi-quantification of mRNA Expression as a Useful Toxicological Endpoint for the Identification of Embryotoxic/Teratogenic Substances

30 July 2024

4

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Struggles for equivalence: in vitro developmental toxicity model evolution in pharmaceuticals in 2006.

30 July 2024

6

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Endless possibilities: stem cells and the vision for toxicology testing in the 21st century

30 July 2024

7

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

30 July 2024

8

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds.

30 July 2024

9

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells

30 July 2024

10

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

30 July 2024

11

1 reference

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Detection limits of different approaches in behavioral teratology, and correlation of effects with neurochemical parameters

30 July 2024

12

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Characterization of the developmental toxicity of di-n-butyl phthalate in rats.

30 July 2024

13

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Developmental toxicity evaluation of mono-n-butyl phthalate in rats.

30 July 2024

14

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

A category approach for reproductive effects of phthalates

30 July 2024

16

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model

30 July 2024

17

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Mode of action for reproductive and hepatic toxicity inferred from a genomic study of triazole antifungals.

30 July 2024

20

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

A modular approach to the ECVAM principles on test validity.

30 July 2024

21

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Exposure of the pregnant rat to warfarin and vitamin K1: an animal model of intraventricular hemorrhage in the fetus

30 July 2024

22

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Pattern of malformations in the children of women treated with carbamazepine during pregnancy

30 July 2024

23

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Embryotoxicity of the folate antagonist methotrexate in rats and rabbits

30 July 2024

24

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Strain differences in response of Sprague-Dawley and Long Evans Hooded rats to the teratogen nitrofen

30 July 2024

25

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-octyl phthalate

30 July 2024

26

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Effects of the high methylmercury dose used in the collaborative behavioral teratology study on brain anatomy

30 July 2024

27

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation

30 July 2024

29

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

30 July 2024

32

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test

30 July 2024

33

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Transcriptome analysis of mouse stem cells and early embryos

30 July 2024

34

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Dose-response modeling of continuous endpoints.

30 July 2024

35

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

30 July 2024

Warfarin as teratogen

36

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

30 July 2024

37

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate

30 July 2024

38

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

30 July 2024

39

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Disentangling cellular proliferation and differentiation in the embryonic stem cell test, and its impact on the experimental protocol.

30 July 2024

40

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

Teratogenic potential of di- and mono-(2-ethylhexyl)phthalate in mice

30 July 2024

41

1 reference

https://api.crossref.org/works/10.1093/TOXSCI/KFQ291

30 July 2024

Identifiers

1 reference

17 April 2018

1 reference

17 April 2018