Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. (Q51965126)

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scientific article published on 28 April 2008

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English	Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6.	scientific article published on 28 April 2008

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scholarly article

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6 January 2020

Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6 (English)

1 reference

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6 January 2020

toll-like receptor

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5

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6 January 2020

Yolande Richard

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6 January 2020

Fabrice Cognasse

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Fabrice Cognasse

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6 January 2020

Olivier Garraud

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Olivier Garraud

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6 January 2020

Hind Hamzeh-Cognasse

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Hind Hamzeh-Cognasse

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6 January 2020

Patricia Chavarin

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Patricia Chavarin

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6 January 2020

author name string

Sandrine Lafarge

3

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publication date

28 April 2008

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6 January 2020

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6 January 2020

125

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6 January 2020

3

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6 January 2020

430-437

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6 January 2020

CpG drives human transitional B cells to terminal differentiation and production of natural antibodies

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TLR9 stimulation drives naïve B cells to proliferate and to attain enhanced antigen presenting function.

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CpG DNA activation and plasma-cell differentiation of CD27- naive human B cells

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Human monocyte-derived dendritic cells express TLR9 and react directly to the CpG-A oligonucleotide D19.

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CD19 function in central and peripheral B-cell development

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Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells

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Poly-guanosine strings improve cellular uptake and stimulatory activity of phosphodiester CpG oligonucleotides in human leukocytes

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CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.

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Toll-like receptor ligands directly promote activated CD4+ T cell survival

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IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

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Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow.

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Functional analysis of human memory B-cell subpopulations: IgD+CD27+ B cells are crucial in secondary immune response by producing high affinity IgM.

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The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

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Distinct response of human B cell subpopulations in recognition of an innate immune signal, CpG DNA.

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Role of mitogen-activated protein kinases in CpG DNA-mediated IL-10 and IL-12 production: central role of extracellular signal-regulated kinase in the negative feedback loop of the CpG DNA-mediated Th1 response

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1 reference

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Expression of toll-like receptors on B lymphocytes

1 reference

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Identifiers

10.1111/J.1365-2567.2008.02844.X

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6 January 2020

PMC publication ID

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1 reference

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6 January 2020

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