Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. (Q51981842)

19 April 2018

title

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. (English)

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19 April 2018

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3

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19 April 2018

Klaus Rajewsky

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19 April 2018

author name string

Ulf Klein

1

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19 April 2018

Stefano Casola

2

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Qiong Shen

4

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19 April 2018

Marie Lia

5

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19 April 2018

Tongwei Mo

6

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19 April 2018

Thomas Ludwig

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Riccardo Dalla-Favera

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language of work or name

English

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publication date

11 June 2006

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19 April 2018

published in

Nature Immunology

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volume

7

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19 April 2018

page(s)

773-782

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19 April 2018

issue

7

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19 April 2018

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Clonal selection and learning in the antibody system

21 January 2018

1 reference

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

21 January 2018

1 reference

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

21 January 2018

1 reference

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

21 January 2018

1 reference

Cutting edge: polycomb gene expression patterns reflect distinct B cell differentiation stages in human germinal centers.

21 January 2018

1 reference

Tracking CD40 signaling during germinal center development

21 January 2018

1 reference

Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells.

21 January 2018

1 reference

STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression

21 January 2018

1 reference

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

1 reference

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator

21 January 2018

1 reference

Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE).

21 January 2018

1 reference

A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes

21 January 2018

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Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

21 January 2018

1 reference

Interferon regulatory factors: the next generation

21 January 2018

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The role of IRF-4 in B and T cell activation and differentiation

21 January 2018

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The role of IRF-4 in transcriptional regulation

21 January 2018

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E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII).

21 January 2018

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Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4

21 January 2018

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IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

21 January 2018

1 reference

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

21 January 2018

1 reference

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

21 January 2018

1 reference

Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting

21 January 2018

1 reference

Germinal centre B cells: antigen specificity and changes in heavy chain class expression.

21 January 2018

1 reference

Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.

21 January 2018

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XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

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Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

1 reference

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

21 January 2018

1 reference

Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s)

21 January 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

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A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

21 January 2018

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Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

21 January 2018

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Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.

21 January 2018

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The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

21 January 2018

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Antigen-driven B cell differentiation in vivo

21 January 2018

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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

21 January 2018

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Transcriptional analysis of the B cell germinal center reaction

21 January 2018

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Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells

21 January 2018

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Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

21 January 2018

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Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation

21 January 2018

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The balance between Pax5 and Id2 activities is the key to AID gene expression

21 January 2018

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Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.

21 January 2018

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Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

21 January 2018

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PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage

21 January 2018

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Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching

21 January 2018

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AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

21 January 2018

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Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Widespread recombinase expression using FLPeR (flipper) mice

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

B lymphocytes express and lose syndecan at specific stages of differentiation

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1357

1 reference

19 April 2018

PubMed ID

16767092

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19 April 2018