Cyclin D1 (Q5198270)

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mammalian protein found in Homo sapiens
  • BCL-1
  • PRAD1 oncogene
  • G1/S-specific cyclin-D1
  • B-cell lymphoma 1 protein
  • BCL-1 oncogene
  • B-cell CLL/lymphoma 1
  • CCND1
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Language Label Description Also known as
English
Cyclin D1
mammalian protein found in Homo sapiens
  • BCL-1
  • PRAD1 oncogene
  • G1/S-specific cyclin-D1
  • B-cell lymphoma 1 protein
  • BCL-1 oncogene
  • B-cell CLL/lymphoma 1
  • CCND1

Statements

molecular function
protein binding
determination method
IPI
29 references
retrieved
1 January 2018
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
UniProt
UniProt protein ID
P24385
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
GOA
curator
UniProt
UniProt protein ID
P24385
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cyclin-binding motifs are essential for the function of p21CIP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Self-assembling protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
New functional activities for the p21 family of CDK inhibitors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Crystal structure of human CDK4 in complex with a D-type cyclin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Isolation and characterization of cytoplasmic cyclin D1 mutants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Functional characterization of human PFTK1 as a cyclin-dependent kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
retrieved
1 January 2018
stated in
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24385
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE CCND1 208712 at fs.png
732 × 530; 10 KB
0 references

Identifiers

 
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