Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras. (Q52008070)

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scientific article published on 2 May 2003

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English	Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.	scientific article published on 2 May 2003

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3 November 2019

Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras (English)

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3 November 2019

neurofibromatosis type I

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2

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3 November 2019

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Shunji Yunoue

1

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3 November 2019

Kohji Fukunaga

3

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3 November 2019

Liping Feng

4

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3 November 2019

Tatsuya Ozawa

5

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3 November 2019

Toru Nishi

6

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3 November 2019

Akira Kikuchi

7

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3 November 2019

Seisuke Hattori

8

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3 November 2019

Junichi Kuratsu

9

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3 November 2019

Hideyuki Saya

10

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3 November 2019

Norie Araki

11

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3 November 2019

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2 May 2003

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3 November 2019

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12

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Journal of Biological Chemistry

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3 November 2019

278

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3 November 2019

29

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3 November 2019

26958-26969

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3 November 2019

Linkage studies with chromosome 17 DNA markers in 45 neurofibromatosis 1 families

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

NF1 mRNA isoform expression in PC12 cells: modulation by extrinsic factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

A mouse model for the learning and memory deficits associated with neurofibromatosis type I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Signaling pathways for PC12 cell differentiation: making the right connections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Phosphorylation of neurofibromatosis type 1 gene product (neurofibromin) by cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Activation of R-Ras GTPase by GTPase-activating proteins for Ras, Gap1(m), and p120GAP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

A rapid and efficient one-tube PCR-based mutagenesis technique using Pfu DNA polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Structural analysis of the GAP-related domain from neurofibromin and its implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Characterization of a factor that stimulates hydrolysis of GTP bound to ras gene product p21 (GTPase-activating protein) and correlation of its activity to cell density

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Contrasting levels of p21ras activation and expression of neurofibromin in peripheral primitive neuroectodermal tumour and neuroblastoma cells, and their response to retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Selective regulation of agrin mRNA induction and alternative splicing in PC12 cells by Ras-dependent actions of nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209413200

21 January 2018

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