T cells down-modulate peptide-MHC complexes on APCs in vivo. (Q52016064)

19 April 2018

title

T cells down-modulate peptide-MHC complexes on APCs in vivo. (English)

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19 April 2018

Brian C Schaefer

2

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Philippa Marrack

object named as

Philippa Marrack

series ordinal

4

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John Kappler

series ordinal

3

object named as

John W Kappler

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19 April 2018

1

Ross M Kedl

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19 April 2018

language of work or name

English

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publication date

3 December 2001

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19 April 2018

published in

Nature Immunology

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19 April 2018

volume

3

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19 April 2018

page(s)

27-32

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19 April 2018

issue

1

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19 April 2018

https://scigraph.springernature.com/pub.10.1038/ni742

exact match

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cites work

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T cells compete for access to antigen-bearing antigen-presenting cells

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Anergic T cells actively suppress T cell responses via the antigen-presenting cell

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TCR-Mediated internalization of peptide-MHC complexes acquired by T cells

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Cutting edge: CTLs rapidly capture membrane fragments from target cells in a TCR signaling-dependent manner

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T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells

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7 January 2021

Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.

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7 January 2021

Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding

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Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition.

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7 January 2021

Evidence for a differential avidity model of T cell selection in the thymus

1 reference

7 January 2021

Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo

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7 January 2021

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

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7 January 2021

T cell receptor antagonist peptides induce positive selection

1 reference

7 January 2021

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

1 reference

7 January 2021

In vivo priming of two distinct antitumor effector populations: the role of MHC class I expression

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI742

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19 April 2018

Dimensions Publication ID

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19 April 2018