Early changes in behavior deficits, amyloid beta-42 deposits and MAPK activation in doubly transgenic mice co-expressing NSE-controlled human mutant PS2 and APPsw. (Q52040502)

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scientific article published in August 2005

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English	Early changes in behavior deficits, amyloid beta-42 deposits and MAPK activation in doubly transgenic mice co-expressing NSE-controlled human mutant PS2 and APPsw.	scientific article published in August 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Early changes in behavior deficits, amyloid beta-42 deposits and MAPK activation in doubly transgenic mice co-expressing NSE-controlled human mutant PS2 and APPsw. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

author name string

Dae Y Hwang

1

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Jung S Cho

2

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Jae H Oh

3

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Sun B Shim

4

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Seung W Jee

5

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Su H Lee

6

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Su J Seo

7

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Chi W Song

8

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Seok H Lee

9

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Yong K Kim

10

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

publication date

1 August 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Cellular and Molecular Neurobiology

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

25

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Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

5

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

881-898

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-4950-X

21 January 2018

Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-4950-X

21 January 2018

Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reorganization of cingulate cortex in Alzheimer's disease: neuron loss, neuritic plaques, and muscarinic receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Place navigation impaired in rats with hippocampal lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MAPK cascade is required for mammalian associative learning

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK activation is associated with intracellular beta-amyloid accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presenilins in Alzheimer's disease--proteolysis holds the key.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16133940

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10571-005-4950-X

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 April 2018

http://europepmc.org/abstract/MED/16133940

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